ArticleNeuroscience and behavioral physiology
Conditioned defensive reflex in the edible snail (molecular-genetic aspects).
Article in Neuroscience and behavioral physiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
1 citing paper in PubMed, 2 citations in OpenAlex.
- Protein synthesis inhibitors, gene superinduction and memory: too little or too much protein?Neurobiology of learning and memory · 2008Review
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The expression of the early genes c-fos and c-jun were studied by blot hybridization in the central nervous system of the edible snail at the consolidation stage of a conditioned defensive reflex, with the aim of investigating genomic activity in neurons during learning. The c-fos gene was shown to be present in the Helix central nervous system, and its expression was shown to increase significantly during learning. Superinduction of the c-fos gene was observed in the presence of cycloheximide, a protein synthesis inhibitor. Corasol also induced this gene. Thus, induction of the c-fos gene in Helix can be induced by agents which induce it in higher vertebrates. This suggests that expression of the c-fos gene in Helix and in higher vertebrates is regulated by closely related mechanisms. Expression of the c-jun gene was insignificant, and definitive conclusions with regard to the role of this gene in learning cannot be drawn.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.