ArticleThe Journal of physiology1997
Simultaneous measurement of intracellular Ca2+ and asynchronous transmitter release from the same crayfish bouton.
Article in The Journal of physiology, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
What it found
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Who cites it
36 citing papers in PubMed.
- Prolonged synaptic currents increase relay neuron firing at the developing retinogeniculate synapse.Journal of neurophysiology · 2014Article
- An alien divalent ion reveals a major role for Ca²⁺ buffering in controlling slow transmitter release.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014Article
- Calcium cooperativity of exocytosis as a measure of Ca²+ channel domain overlap.Brain research · 2011Review
- Synaptic scaling stabilizes persistent activity driven by asynchronous neurotransmitter release.Neural computation · 2011Article
- Shunting inhibition controls the gain modulation mediated by asynchronous neurotransmitter release in early development.PLoS computational biology · 2010Article
- Control of neurotransmitter release: From Ca2+ to voltage dependent G-protein coupled receptors.Pflugers Archiv : European journal of physiology · 2010Review
- Cellular calcium deficiency plays a role in neuronal death caused by proteasome inhibitors.Journal of neurochemistry · 2009Article
- Molecular mechanisms that control initiation and termination of physiological depolarization-evoked transmitter release.Proceedings of the National Academy of Sciences of the United States of America · 2008Article
- Article
- Integration of asynchronously released quanta prolongs the postsynaptic spike window.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2007Article
- Long-term in vivo modulation of synaptic efficacy at the neuromuscular junction of Rana pipiens frogs.The Journal of physiology · 2005Article
- Post-tetanic potentiation in the rat calyx of Held synapse.The Journal of physiology · 2005Article
- Calcium sensitivity of neurotransmitter release differs at phasic and tonic synapses.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2005Article
- Frequency-dependent modulation of retinogeniculate transmission by serotonin.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2004Article
- Dendritically released transmitters cooperate via autocrine and retrograde actions to inhibit afferent excitation in rat brain.The Journal of physiology · 2004Article
- Stimulation-induced mitochondrial [Ca2+] elevations in mouse motor terminals: comparison of wild-type with SOD1-G93A.The Journal of physiology · 2003Article
- Intraterminal Ca2+ concentration and asynchronous transmitter release at single GABAergic boutons in rat collicular cultures.The Journal of physiology · 2003Article
- Mitochondrial Ca2+ uptake prevents desynchronization of quantal release and minimizes depletion during repetitive stimulation of mouse motor nerve terminals.The Journal of physiology · 2003Article
- New and corrected simulations of synaptic facilitation.Biophysical journal · 2002Article
- Ca2+-independent feedback inhibition of acetylcholine release in frog neuromuscular junction.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2002Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
1. A technique has been developed to monitor neurotransmitter release simultaneously with intracellular Ca2+ concentration ([Ca2+]i) in single release boutons whose diameters range from 3 to 5 microns. 2. Using this technique, we have found a highly non-linear relationship between the rate of asynchronous release and [Ca2+]i. The Hill coefficient lies between 3 and 4. 3. The affinity (Kd) of the putative release-related Ca2+ receptor for asynchronous release was calculated to be in the range of 2-4 microM. 4. The same range of values of Hill coefficient and Kd were obtained when [Ca2+]i was elevated both by bath application of ionomycin and by repetitive stimulation at high frequency. 5. Our results show that the Ca2+ receptor(s) associated with asynchronous release exhibits high affinity for Ca2+.
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