ReviewMolecular biology of the cell1997
Keith R. Porter Lecture, 1996. Of mice and men: genetic disorders of the cytoskeleton.
Review in Molecular biology of the cell, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed.
- Mechanisms mediating the vesicant actions of sulfur mustard after cutaneous exposure.Toxicological sciences : an official journal of the Society of Toxicology · 2010Review
- Morphologic and molecular characterization of two novel Krt71 (Krt2-6g) mutations: Krt71rco12 and Krt71rco13.Mammalian genome : official journal of the International Mammalian Genome Society · 2006Article
- Upregulation of P2Y2 receptors by retinoids in normal human epidermal keratinocytes.Purinergic signalling · 2006Article
- Recessive epidermolysis bullosa simplex phenotype reproduced in vitro: ablation of keratin 14 is partially compensated by keratin 17.The American journal of pathology · 2003Article
- Type II keratins are phosphorylated on a unique motif during stress and mitosis in tissues and cultured cells.Molecular biology of the cell · 2002Article
- Inhibition of protein kinase B (PKB) and PKCzeta mediates keratin K10-induced cell cycle arrest.Molecular and cellular biology · 2001Article
- Defining the regulatory factors required for epidermal gene expression.Molecular and cellular biology · 2000Article
- Cytokeratins of the stratum medium and stratum internum of the equine hoof wall in acute laminitis.Acta veterinaria Scandinavica · 2000Article
- Modulation of cell proliferation by cytokeratins K10 and K16.Molecular and cellular biology · 1999Article
- Differences in the width of the intercellular spaces in the epithelial basal infolding and the renal glomerular filtration site between freeze-substitution and conventional fixation.Journal of anatomy · 1999Article
- 5-Lipoxygenase expression in Langerhans cells of normal human epidermis.Proceedings of the National Academy of Sciences of the United States of America · 1998Article
- Experimental autoimmune encephalomyelitis in mice lacking glial fibrillary acidic protein is characterized by a more severe clinical course and an infiltrative central nervous system lesion.The American journal of pathology · 1998Article
- Caspase cleavage of keratin 18 and reorganization of intermediate filaments during epithelial cell apoptosis.The Journal of cell biology · 1997Article
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Since the time when I was a postdoctoral fellow under the supervision of Dr. Howard Green, then at the Massachusetts Institute of Technology, I have been interested in understanding the molecular mechanisms underlying growth, differentiation, and development in the mammalian ectoderm. The ectoderm gives rise to epidermal keratinocytes and to neurons, which are the only two cell types of the body that devote most of their protein-synthesizing machinery to developing an elaborate cytoskeletal architecture composed of 10-nm intermediate filaments (IFs). Our interest is in understanding the architecture of the cytoskeleton in keratinocytes and in neurons, and in elucidating how perturbations in this architecture can lead to degenerative diseases of the skin and the nervous system. I will concentrate on the intermediate filament network of the skin and its associated genetic disorders, since this has been a long-standing interest of my laboratory at the University of Chicago.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.