ReviewMicrobiology and molecular biology reviews : MMBR1997
Nucleocytoplasmic transport of macromolecules.
Review in Microbiology and molecular biology reviews : MMBR, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
81 citing papers in PubMed.
- The importin-alpha superfamily engages in ethylene signaling by shuttling ETHYLENE INSENSITIVE 2 from the endoplasmic reticulum to the nucleus.The FEBS journal · 2026Article
- Brief and Diverse Excitotoxic Insults Increase the Neuronal Nuclear Membrane Permeability in the Neonatal Brain, Resulting in Neuronal Dysfunction and Cell Death.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Nucleoporin 107 is a prognostic biomarker in hepatocellular carcinoma associated with immune infiltration.Cancer medicine · 2023Article
- Review
- A Novel Effector Protein of Apple Proliferation Phytoplasma Disrupts Cell Integrity ofInternational journal of molecular sciences · 2019Article
- Intracellular Protein Shuttling: A Mechanism Relevant for Myelin Repair in Multiple Sclerosis?International journal of molecular sciences · 2015Review
- Identification and functional characterization of Bet protein as a negative regulator of BFV3026 replication.Virus genes · 2014Article
- High-resolution three-dimensional mapping of mRNA export through the nuclear pore.Nature communications · 2013Article
- Calcium regulation of nucleocytoplasmic transport.Protein & cell · 2011Review
- Cargo surface hydrophobicity is sufficient to overcome the nuclear pore complex selectivity barrier.The EMBO journal · 2009Article
- The roles of multiple importins for nuclear import of murine aristaless-related homeobox protein.The Journal of biological chemistry · 2009Article
- Nuclear import and export of Venezuelan equine encephalitis virus nonstructural protein 2.Journal of virology · 2007Article
- Nuclear export of simian immunodeficiency virus Vpx protein.Journal of virology · 2006Article
- Rb2/p130 and protein phosphatase 2A: key mediators of ovarian carcinoma cell growth suppression by all-trans retinoic acid.Oncogene · 2006Review
- Visualizing single molecules interacting with nuclear pore complexes by narrow-field epifluorescence microscopy.Methods (San Diego, Calif.) · 2006Article
- The capsid protein of beak and feather disease virus binds to the viral DNA and is responsible for transporting the replication-associated protein into the nucleus.Journal of virology · 2006Article
- Simian immunodeficiency virus Vpx is imported into the nucleus via importin alpha-dependent and -independent pathways.Journal of virology · 2006Article
- Predicting protein subcellular localization: past, present, and future.Genomics, proteomics & bioinformatics · 2004Review
- Imaging of single-molecule translocation through nuclear pore complexes.Proceedings of the National Academy of Sciences of the United States of America · 2004Article
- The pseudorabies virus serine/threonine kinase Us3 contains mitochondrial, nuclear and membrane localization signals.Virus genes · 2004Article
21 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nucleocytoplasmic transport is a complex process that consists of the movement of numerous macromolecules back and forth across the nuclear envelope. All macromolecules that move in and out of the nucleus do so via nuclear pore complexes that form large proteinaceous channels in the nuclear envelope. In addition to nuclear pores, nuclear transport of macromolecules requires a number of soluble factors that are found both in the cytoplasm and in the nucleus. A combination of biochemical, genetic, and cell biological approaches have been used to identify and characterize the various components of the nuclear transport machinery. Recent studies have shown that both import to and export from the nucleus are mediated by signals found within the transport substrates. Several studies have demonstrated that these signals are recognized by soluble factors that target these substrates to the nuclear pore. Once substrates have been directed to the pore, most transport events depend on a cycle of GTP hydrolysis mediated by the small Ras-like GTPase, Ran, as well as other proteins that regulate the guanine nucleotide-bound state of Ran. Many of the essential factors have been identified, and the challenge that remains is to determine the exact mechanism by which transport occurs. This review attempts to present an integrated view of our current understanding of nuclear transport while highlighting the contributions that have been made through studies with genetic organisms such as the budding yeast, Saccharomyces cerevisiae.
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