ArticleThe Plant cell1997
Salicylic acid activates a 48-kD MAP kinase in tobacco.
Article in The Plant cell, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 165 papers.
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Who cites it
165 citing papers in PubMed, 508 citations in OpenAlex.
- Decoding MAPK cascades in plant immunity: Activation, regulation, integration, and pathogen manipulation.Journal of integrative plant biology · 2026Review
- Mutagenesis of OsNRAMP5 Affects Blast Resistance Through Mn Absorption in Rice.Rice (New York, N.Y.) · 2025Article
- Identification of MAPK Genes inInternational journal of molecular sciences · 2024Article
- Natural variation in the pattern-triggered immunity response in plants: Investigations, implications and applications.Molecular plant pathology · 2024Review
- Spermine inhibits PAMP-induced ROS and Ca2+ burst and reshapes the transcriptional landscape of PAMP-triggered immunity in Arabidopsis.Journal of experimental botany · 2023Article
- Phosphorylation of the auxin signaling transcriptional repressor IAA15 by MPKs is required for the suppression of root development under drought stress in Arabidopsis.Nucleic acids research · 2022Article
- Protein kinase sensors: an overview of new designs for visualizing kinase dynamics in single plant cells.Plant physiology · 2021Review
- Computational Systems Biology of Alfalfa - Bacterial Blight Host-Pathogen Interactions: Uncovering the Complex Molecular Networks for Developing Durable Disease Resistant Crop.Frontiers in plant science · 2021Article
- Gene Mapping, Genome-Wide Transcriptome Analysis, and WGCNA Reveals the Molecular Mechanism for Triggering Programmed Cell Death in Rice MutantPlants (Basel, Switzerland) · 2020Article
- Organized Disassembly of Photosynthesis During Programmed Cell Death Mediated By Long Chain Bases.Scientific reports · 2020Article
- From Survival to Productivity Mode: Cytokinins Allow Avoiding the Avoidance Strategy Under Stress Conditions.Frontiers in plant science · 2020Article
- Copper treatment of peach leaves causes lesion formation similar to the biotic stress response.Plant biotechnology (Tokyo, Japan) · 2019Article
- Identification of Msp1-Induced Signaling Components in Rice Leaves by Integrated Proteomic and Phosphoproteomic Analysis.International journal of molecular sciences · 2019Article
- CaMPK9 increases the stability of CaWRKY40 transcription factor which triggers defense response in chickpea upon Fusarium oxysporum f. sp. ciceri Race1 infection.Plant molecular biology · 2019Article
- Jasmonic acid-induced hydrogen sulfide activates MEK1/2 in regulating the redox state of ascorbate inPlant signaling & behavior · 2019Article
- Article
- Identification of Regulatory Networks of MicroRNAs and Their Targets in Response toFrontiers in plant science · 2019Article
- The Polyamine Putrescine Contributes to HFrontiers in plant science · 2019Article
- The MAPK Kinase Kinase GmMEKK1 Regulates Cell Death and Defense Responses.Plant physiology · 2018Article
- 2,4-D and dicamba resistance mechanisms in wild radish: subtle, complex and population specific?Annals of botany · 2018Article
105 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The involvement of phosphorylation/dephosphorylation in the salicylic acid (SA) signal transduction pathway leading to pathogenesis-related gene induction has previously been demonstrated using kinase and phosphatase inhibitors. Here, we show that in tobacco suspension cells, SA induced a rapid and transient activation of a 48-kD kinase that uses myelin basic protein as a substrate. This kinase is called the p48 SIP kinase (for SA-Induced Protein kinase). Biologically active analogs of SA, which induce pathogenesis-related genes and enhanced resistance, also activated this kinase, whereas inactive analogs did not. Phosphorylation of a tyrosine residue(s) in the SIP kinase was associated with its activation. The SIP kinase was purified to homogeneity from SA-treated tobacco suspension culture cells. The purified SIP kinase is strongly phosphorylated on a tyrosine residue(s), and treatment with either protein tyrosine or serine/threonine phosphatases abolished its activity. Using primers corresponding to the sequences of internal tryptic peptides, we cloned the SIP kinase gene. Analysis of the SIP kinase sequence indicates that it belongs to the MAP kinase family and that it is distinct from the other plant MAP kinases previously implicated in stress responses, suggesting that different members of the MAP kinase family are activated by different stresses.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.