Evidence map›Paper›PMID 9163481›Full record

ArticleJournal of clinical microbiology1997

Human disease in Europe caused by a granulocytic Ehrlichia species.

M Petrovec, S Lotric Furlan, T A Zupanc, F Strle, P Brouqui, V Roux, J S Dumler

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Journal of clinical microbiology, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 91 papers.

0numbers the graph read from it
0cells of the map it votes in
91citing papers in PubMed
13.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

91 citing papers in PubMed, 310 citations in OpenAlex.

  1. Article
  2. Tick-Borne Bacterial Diseases in Europe: Threats to public health.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2024
    Review
  3. Article
  4. Pathogens (Basel, Switzerland) · 2023
    Article
  5. Molecular Detection ofMicroorganisms · 2022
    Article
  6. Article
  7. Article
  8. Ecotyping ofAnimals : an open access journal from MDPI · 2021
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Prevalence and co-infection with tick-borneInternational journal for parasitology. Parasites and wildlife · 2019
    Article
  14. Article
  15. Human Granulocytic Anaplasmosis as a Cause of Febrile Illness in Korea Since at Least 2006.The American journal of tropical medicine and hygiene · 2017
    Article
  16. Article
  17. Detection of a Novel Ehrlichia Species in Haemaphysalis longicornis Tick from China.Vector borne and zoonotic diseases (Larchmont, N.Y.) · 2016
    Article
  18. Article
  19. Article
  20. Review

31 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

M PetrovecInstitute of Microbiology and Immunology, Medical Faculty, University of Ljubljana, Slovenia. Mirc.Petrovec@mf.uni-lj.si
S Lotric Furlan
T A Zupanc
F Strle
P Brouqui
V Roux
J S Dumler
University of Ljubljana · SI

Funding

Virulence and Immunity of Granulocytic EhrlichiaeR01AI041213 · NIAID · JOHNS HOPKINS UNIVERSITY · PI DUMLER, JOHN STEPHEN · 1996 to 2005
$1.3M
NIAID NIH HHS R01 AI41213
6 · The paper itself

Abstract

Human granulocytic ehrlichiosis (HGE) was recently described in North America. It is caused by an Ehrlichia species closely related to Ehrlichia phagocytophila and Ehrlichia equi, recognized to infect mostly ruminants and horses, respectively. The vector in North America is the tick Ixodes scapularis, which is also the vector of the Lyme disease agent, Borrelia burgdorferi. Previous serologic studies in patients with a diagnosis of Lyme borreliosis indicate that HGE may exist in Europe. We report the first documented case of HGE in Europe. The diagnosis was established by seroconversion to E. equi and the HGE agent and by PCR with sequence analysis of the gene encoding the HGE agent 16S rRNA. Interestingly, the patient presented with a self-limited but moderately severe illness. Thus, European physicians need to be aware that HGE exists in Europe and that the diagnosis should be considered in febrile patients with tick bites in areas where Lyme disease is endemic.

Indexed as

Antibodies, BacterialDNA, BacterialEhrlichiaEhrlichia chaffeensisEhrlichiosisFemaleGranulocytesHumansMiddle AgedMolecular Sequence DataPolymerase Chain ReactionRNA, BacterialRNA, Ribosomal, 16SSequence Analysis, DNASequence Homology, Nucleic AcidSloveniaAntibodies, BacterialDNA, BacterialRNA, BacterialRNA, Ribosomal, 16S

Identifiers

PMID9163481
PMCPMC229786
OpenAlexW1486304048

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.