ArticleAmerican journal of human genetics1997
A gene for autosomal dominant nonsyndromic hearing loss (DFNA12) maps to chromosome 11q22-24.
Article in American journal of human genetics, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Research progress in pathogenic genes of hereditary non-syndromic mid-frequency deafness.Frontiers of medicine · 2016Review
- Whole-exome sequencing identifies a novel genotype-phenotype correlation in the entactin domain of the known deafness gene TECTA.PloS one · 2014Article
- Audiological evaluation of affected members from a Dutch DFNA8/12 (TECTA) family.Journal of the Association for Research in Otolaryngology : JARO · 2007Article
- A novel TECTA mutation in a Dutch DFNA8/12 family confirms genotype-phenotype correlation.Journal of the Association for Research in Otolaryngology : JARO · 2006Article
- A gene for fluctuating, progressive autosomal dominant nonsyndromic hearing loss, DFNA16, maps to chromosome 2q23-24.3.American journal of human genetics · 1999Article
- A unique point mutation in the PMP22 gene is associated with Charcot-Marie-Tooth disease and deafness.American journal of human genetics · 1999Article
- A novel locus for autosomal dominant nonsyndromic hearing loss, DFNA13, maps to chromosome 6p.American journal of human genetics · 1997Article
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We performed linkage analysis in a Belgian family with autosomal dominant midfrequency hearing loss, which has a prelingual onset and a nonprogressive course in most patients. We found LOD scores >6 with markers on chromosome 11q. Analysis of key recombinants maps this deafness gene (DFNA12) to a 36-cM interval on chromosome 11q22-24, between markers D11S4120 and D11S912. The critical regions for the recessive deafness locus DFNB2 and the dominant locus DFNA11, which were previously localized to the long arm of chromosome 11, do not overlap with the candidate interval of DFNA12.
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9150164PMC1712440What OpenQuestion holds
Registered trials
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