ArticleVirus research1997
Bovine coronavirus I protein synthesis follows ribosomal scanning on the bicistronic N mRNA.
Article in Virus research, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed.
- Betacoronavirus internal protein: role in immune evasion and viral pathogenesis.Journal of virology · 2025Review
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- Hydrophobic Alpha-Helical Short Peptides in Overlapping Reading Frames of the Coronavirus Genome.Pathogens (Basel, Switzerland) · 2022Article
- Article
- Ribosomal control in RNA virus-infected cells.Frontiers in microbiology · 2022Review
- One microRNA has the potential to target whole viral mRNAs in a given human coronavirus.Frontiers in microbiology · 2022Review
- Translational control of coronaviruses.Nucleic acids research · 2020Review
- The interface between coronaviruses and host cell RNA biology: Novel potential insights for future therapeutic intervention.Wiley interdisciplinary reviews. RNA · 2020Review
- Intra-genome variability in the dinucleotide composition of SARS-CoV-2.Virus evolution · 2020Article
- Review
- Viral and Cellular mRNA Translation in Coronavirus-Infected Cells.Advances in virus research · 2016Review
- Acquisition of new protein domains by coronaviruses: analysis of overlapping genes coding for proteins N and 9b in SARS coronavirus.Virus genes · 2015Article
- Article
- Article
- Culturing the unculturable: human coronavirus HKU1 infects, replicates, and produces progeny virions in human ciliated airway epithelial cell cultures.Journal of virology · 2010Article
- Severe acute respiratory syndrome coronavirus accessory protein 9b is a virion-associated protein.Virology · 2009Article
- Mouse hepatitis coronavirus A59 nucleocapsid protein is a type I interferon antagonist.Journal of virology · 2007Article
- The ORF7b protein of severe acute respiratory syndrome coronavirus (SARS-CoV) is expressed in virus-infected cells and incorporated into SARS-CoV particles.Journal of virology · 2007Article
- Understanding the accessory viral proteins unique to the severe acute respiratory syndrome (SARS) coronavirus.Antiviral research · 2006Review
- Article
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Authors and funding
2 authors.
Funding
Abstract
The mRNA encoding the 49-kDa nucleocapsid protein (N) of the bovine coronavirus is bicistronic. A 23-kDa protein, termed the I protein for the 'internal' open reading frame (ORF), is also synthetized but in the +1 reading frame beginning 61 nt downstream of the N start codon. Sequences flanking the N and I start codons suggest that the I ORF might be accessed by scanning ribosomes passing over the N start codon. Here we test this idea and demonstrate with translation studies both in vitro and in vivo that the I protein is synthesized according to the leaky scanning model for initiation of translation on the subgenomic N mRNA molecule.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.