ArticleGenetics1997
Polymorphism and locus-specific effects on polymorphism at microsatellite loci in natural Drosophila melanogaster populations.
Article in Genetics, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed.
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- Radiation-mediated supply of genetic variation outweighs the effects of selection and drift in Chernobyl Daphnia populations.Journal of evolutionary biology · 2022Article
- Evaluation of Cross-Species Transferability of SSR Markers inPlants (Basel, Switzerland) · 2020Article
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- Genetic variation in ecoraces of tropical tasar silkworm, Antheraea mylitta using SSR markers.Journal of genetics · 2016Article
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- Population genomic inferences from sparse high-throughput sequencing of two populations of Drosophila melanogaster.Genome biology and evolution · 2009Article
- Identification of selective sweeps in closely related populations of the house mouse based on microsatellite scans.Genetics · 2008Article
- Comparisons of mutation rate variation at genome-wide microsatellites: evolutionary insights from two cultivated rice and their wild relatives.BMC evolutionary biology · 2008Article
- Similar levels of X-linked and autosomal nucleotide variation in African and non-African populations of Drosophila melanogaster.BMC evolutionary biology · 2007Article
- Identification of selective sweeps using a dynamically adjusted number of linked microsatellites.Genetics · 2007Article
- A Bayesian heterogeneous analysis of variance approach to inferring recent selective sweeps.Genetics · 2006Article
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- African sequence variation accounts for most of the sequence polymorphism in non-African Drosophila melanogaster.Genetics · 2005Article
- Article
- Inferring the population structure and demography of Drosophila ananassae from multilocus data.Genetics · 2004Article
- Factors affecting polymorphism at microsatellite loci in bread wheat [ Triticum aestivum (L.) Thell]: effects of mutation processes and physical distance from the centromere.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2004Article
- Locus-specific genetic differentiation at Rw among warfarin-resistant rat (Rattus norvegicus) populations.Genetics · 2003Article
- Patterns of DNA sequence polymorphism at Sod vicinities in Drosophila melanogaster: unraveling the footprint of a recent selective sweep.Proceedings of the National Academy of Sciences of the United States of America · 2003Article
Corrections and comments
- Erratum issued
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We have studied the natural variation at microsatellite loci in two African and five non-African populations of Drosophila melanogaster. Ten dinucleotide simple sequence loci were cloned from chromosomally mapped P1 clones and typed for single individuals from isofemale lines of the respective populations. We find that the African populations harbor the largest degree of diversity, while the non-African populations show a lower diversity. This supports previous results that D. melanogaster originated in Africa and spread across the rest of the world in historic times. Using genetic distance measures, we find also a distinct population subdivision between the non-African populations. Most interestingly, we find for some loci in some populations a strongly reduced variability, which cannot be explained by bottleneck effects. Employing a conservative test based on the variance in repeat number, we find that at least one locus in one population deviates significantly from the expectations of mutation-drift equilibrium. We suggest that this may be due to a recent selective sweep in this chromosomal region that may have been caused by a linked locus that was involved in local adaptation of the population.
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