Evidence map›Paper›PMID 9135524›Full record

ArticleGut1997

Carcinoma of the ampulla of Vater: prognostic factors after curative surgery: a series of 45 cases.

A Dorandeu, J L Raoul, F Siriser, N Leclercq-Rioux, M Gosselin, E D Martin, M P Ramée, B Launois

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In one paragraph

Article in Gut, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
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  4. Article
  5. Markers of bile duct tumors.World journal of gastrointestinal oncology · 2011
    Article
  6. Usefulness of follow-up after pancreatoduodenectomy for carcinoma of the ampulla of Vater.HPB : the official journal of the International Hepato Pancreato Biliary Association · 2007
    Article
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

A DorandeuService d'Anatomie Pathologique, Centre Régional Hospitalier Universitaire de Rennes, France.
J L Raoul
F Siriser
N Leclercq-Rioux
M Gosselin
E D Martin
M P Ramée
B Launois
Centre Hospitalier Universitaire de Rennes · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSome adjuvant or neoadjuvant therapy could be important for patients operated on for tumours of the ampulla of Vater, especially for those having a higher risk of recurrence.

aimTo evaluate prognostic factors after curative surgery based on a series of 45 cases of malignant tumours of the Oddi sphincter. PATIENTS: From 1970 to 1992, a curative resection was performed in 45 patients (age 62.8 (SD 10.1) years) with adenocarcinoma of the ampulla. Surgical procedures included pancreatoduodenectomy (n = 42) and resection of the ampulla (n = 3). Actuarial survival was 44 (SD 9)% at five years.

methodsVarious prognostic variables were studied: clinical manifestations, macroscopic aspect, differentiation, noninvasive adenomatous component, mucin histochemistry, immunohistochemistry (CEA, CA19.9, p53, Ki67), and accepted classifications (Blumgart and Kennedy, Martin, Yamaguchi and Enjoji, Talbot et al, pTNM).

resultsVariables with prognostic power, in order of importance were: Classification of Talbot et al; CA19.9; pTNM; sialomucins; classification of Yamaguchi and Ejoji; Martin classification; sulphomucins; non-invasive adenomatous component (positive > negative); jaundice; tumour localisation.

conclusionsThis series confirmed the prognostic power of former classifications and showed the prognostic power of other variables (mucin, non-invasive adenomatous component, CA19.9).

Indexed as

Ampulla of VaterAdenocarcinomaAdolescentAdultAgedAged, 80 and overBiomarkers, TumorCA-19-9 AntigenCarcinoembryonic AntigenCommon Bile Duct NeoplasmsFemaleHumansImmunohistochemistryKi-67 AntigenMaleMiddle AgedBiomarkers, TumorCA-19-9 AntigenCarcinoembryonic AntigenKi-67 AntigenMucinsTumor Suppressor Protein p53

Identifiers

PMID9135524
PMCPMC1027085
OpenAlexW2170824011

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.