ReviewJournal of bioenergetics and biomembranes1996
Importance of mitochondrial transmembrane processes in human mitochondriopathies.
Review in Journal of bioenergetics and biomembranes, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 18 citations in OpenAlex.
- Vdac1 Downregulation Causes Mitochondrial Disintegration Leading to Hippocampal Neurodegeneration in Scopolamine-Induced Amnesic Mice.Molecular neurobiology · 2019Article
- VDAC3 As a Potential Marker of Mitochondrial Status Is Involved in Cancer and Pathology.Frontiers in oncology · 2016Review
- Identifying differential exon splicing using linear models and correlation coefficients.BMC bioinformatics · 2009Article
- Upregulation of the mitochondrial phosphate carrier during freezing in the wood frog Rana sylvatica: potential roles of transporters in freeze tolerance.Journal of bioenergetics and biomembranes · 2004Article
- Human mitochondrial transmembrane metabolite carriers: tissue distribution and its implication for mitochondrial disorders.Journal of bioenergetics and biomembranes · 1998Article
- Drosophila male-specific lethal-2 protein: structure/function analysis and dependence on MSL-1 for chromosome association.Genetics · 1997Article
- Article
- High resolution respirometry of permeabilized skeletal muscle fibers in the diagnosis of neuromuscular disorders.Molecular and cellular biochemistry · 1997Article
- Mitochondrial channels revisited.Journal of bioenergetics and biomembranes · 1996Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
Abstract
In a substantial group of subjects suspected to have a mitochondriopathy no defect in the mitochondrial energy metabolism (pyruvate dehydrogenase complex or respiratory chain complexes) can be demonstrated. At least in some of these subjects it seems justified to consider a defect in one of the proteins which mediate the transport of several ions and substrates across the mitochondrial membranes. Of particular interest are proteins which are directly involved in the process of oxidative phosphorylation, such as the adenine nucleotide translocator (ANT) and the phosphate carrier (PiC). However, defects in transmembrane ion transporters also may induce impaired energy metabolism probably as a result of osmotic disturbances within the mitochondrial matrix. In this respect, the voltage-dependent anion channel (VDAC) and other ion channels have to be taken into consideration. Here we review the still incomplete knowledge of the occurrence of ANT, PiC, VDAC, cation channels, and a few substrate carriers in human tissues, as well as their possible role in pathology.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.