Trial reportClinical rheumatology1997
Plasma endothelin-1 levels in Behçet's disease.
Trial report in Clinical rheumatology, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- Finding the Needle in the Haystack: Serological and Urinary Biomarkers in Behçet's Disease: A Systematic Review.International journal of molecular sciences · 2023Pooled it
- Delayed Vasospasm after Aneurysmal Subarachnoid Hemorrhage in Behcet Syndrome.Journal of cerebrovascular and endovascular neurosurgery · 2016Article
- Endothelin 1 levels in relation to clinical presentation and outcome of Henoch Schonlein purpura.BMC pediatrics · 2008Article
- Pathogenesis of Adamantiades-Behçet's disease.Medical microbiology and immunology · 2003Review
- Behçet's disease.Postgraduate medical journal · 2000Review
- Increased plasma endothelin-1 levels in active Behçet's disease.Clinical rheumatology · 1997Article
- Assessment of serum homocysteine, endothelin-1, and nitric oxide levels in behçet's disease.Indian journal of dermatologyArticle
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plasma concentrations of endothelin-1 (ET-1), a vasoconstrictor peptide released from vascular endothelial and synovial cells, were measured by radioimmunoassay in 27 patients with Behçet's disease (BD) and 18 healthy controls. The plasma ET-1 concentrations were found to be significantly increased in patients with BD (121.15 +/- 11.6 fmol/dl) compared with the healthy subjects (89.37 +/- 8.03 fmol/dl p < 0.05). The elevation of ET-1 did not correlate with the disease duration, gender, ocular or articular involvement. Whether the elevated ET-1 level is a direct result of its increased synthesis from injured vascular endothelial cells or whether its presence in high concentrations may be responsible, together with other factors for both vascular and articular complications in patients with BD is uncertain.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.