Evidence map›Paper›PMID 9126441›Full record

ReviewEmerging infectious diseases

Mycoplasmas: sophisticated, reemerging, and burdened by their notoriety.

J B Baseman, J G Tully

Open access · diamondAbstract readHistorical ArticleReview
In one paragraph

Review in Emerging infectious diseases. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 100 papers.

0numbers the graph read from it
0cells of the map it votes in
100citing papers in PubMed
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

100 citing papers in PubMed, 345 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Association betweenBiomedical reports · 2024
    Review
  6. Unraveling the adaptive strategies ofFrontiers in cellular and infection microbiology · 2024
    Article
  7. A comprehensive review ofFrontiers in medicine · 2024
    Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. A Review ofFrontiers in veterinary science · 2021
    Review
  14. Article
  15. Frontiers in immunology · 2021
    Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article

40 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

J B BasemanDepartment of Microbiology, University of Texas Health Science Center, San Antonio 78284-7758, USA. baseman@uthscsa.edu
J G Tully
Bipar · FRNational Institutes of Health · US

Funding

MECHANISMS OF MYCOPLASMA CYTADHERENCE AND INVASIONR01AI041010 · NIAID · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI BASEMAN, JOEL BARRY · 1996 to 2007
$2.3M
MOLECULAR ANALYSIS OF ADHESIN P1R01AI027873 · NIAID · UNIVERSITY OF TEXAS HLTH SCI CTR SAN ANT · PI BASEMAN, JOEL BARRY · 1989 to 1993
–
BIOLOGY OF AIDS-RELATED MYCOPLASMASR01AI032829 · NIAID · UNIVERSITY OF TEXAS HLTH SCI CTR SAN ANT · PI BASEMAN, JOEL BARRY · 1992 to 1994
–
NIAID NIH HHS AI 27873NIAID NIH HHS AI 32829NIAID NIH HHS AI 41010
6 · The paper itself

Abstract

Mycoplasmas are most unusual self-replicating bacteria, possessing very small genomes, lacking cell wall components, requiring cholesterol for membrane function and growth, using UGA codon for tryptophan, passing through "bacterial-retaining" filters, and displaying genetic economy that requires a strict dependence on the host for nutrients and refuge. In addition, many of the mycoplasmas pathogenic for humans and animals possess extraordinary specialized tip organelles that mediate their intimate interaction with eucaryotic cells. This host-adapted survival is achieved through surface parasitism of target cells, acquisition of essential biosynthetic precursors, and in some cases, subsequent entry and survival intracellularly. Misconceptions concerning the role of mycoplasmas in disease pathogenesis can be directly attributed to their biological subtleties and to fundamental deficits in understanding their virulence capabilities. In this review, we highlight the biology and pathogenesis of these procaryotes and provide new evidence that may lead to increased appreciation of their role as human pathogens.

Indexed as

AIDS-Related Opportunistic InfectionsAnimalsArthritisBacterial AdhesionCell Transformation, NeoplasticCrohn DiseaseHistory, 20th CenturyHumansImmunologic Deficiency SyndromesMycoplasmaMycoplasma InfectionsMycoplasma pneumoniaePersian Gulf Syndrome

Identifiers

PMID9126441
PMCPMC2627593
OpenAlexW2116583223

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.