ArticleProceedings of the National Academy of Sciences of the United States of America1997
Dual activity maps in primate visual cortex produced by different temporal patterns of zif268 mRNA and protein expression.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 60 citations in OpenAlex.
- Illuminating the Activated Brain: Emerging Activity-Dependent Tools to Capture and Control Functional Neural Circuits.Neuroscience bulletin · 2019Review
- Genetic Reporters of Neuronal Activity: c-Fos and G-CaMP6.Methods in enzymology · 2018Article
- Use of TAI-FISH to visualize neural ensembles activated by multiple stimuli.Nature protocols · 2018Article
- Identification of Eye-Specific Domains and Their Relation to Callosal Connections in Primary Visual Cortex of Long Evans Rats.Cerebral cortex (New York, N.Y. : 1991) · 2015Article
- Mapping the mosaic sequence of primate visual cortical development.Frontiers in neuroanatomy · 2015Article
- Visual system plasticity in mammals: the story of monocular enucleation-induced vision loss.Frontiers in systems neuroscience · 2015Review
- Visualizing an emotional valence map in the limbic forebrain by TAI-FISH.Nature neuroscience · 2014Article
- Divergent motor projections from the pedunculopontine nucleus are differentially regulated in Parkinsonism.Brain structure & function · 2014Article
- Laterality effect for faces in chimpanzees (Pan troglodytes).The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013Article
- Unravelling the development of the visual cortex: implications for plasticity and repair.Journal of anatomy · 2010Review
- Hippocampal cells encode places by forming small anatomical clusters.Neuroscience · 2010Article
- θ burst and conventional low-frequency rTMS differentially affect GABAergic neurotransmission in the rat cortex.Experimental brain research · 2009Article
- High- and low-frequency repetitive transcranial magnetic stimulation differentially activates c-Fos and zif268 protein expression in the rat brain.Experimental brain research · 2008Article
- Experience-dependent plasticity of mouse visual cortex in the absence of the neuronal activity-dependent marker egr1/zif268.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2001Article
- Motion processing in the macaque: revisited with functional magnetic resonance imaging.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2001Article
- Of monkeys and men: vervets and the genetics of human-like behaviors.American journal of human genetics · 1997Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
Abstract
The inducible nature of the immediate-early genes (IEGs) c-fos and zif268 allows their products to be used as activity markers in the brain. The utility of such markers in general is restricted because they can resolve only neurons activated by a single stimulus. To overcome this limitation, we have developed a double-label technique that exploits the dissimilar time course of zif268 mRNA and protein induction, allowing them to be separately induced by two different stimuli and independently stained to provide a visual display of neurons that are responsive to each stimulus. Two powerful features of this new imaging technique-the possibility of staining separate populations of activated neurons and the ability to visualize them at the cellular level-should extend IEG applications in biological activity mapping.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.