ArticleProceedings of the National Academy of Sciences of the United States of America1997
Adult fast myosin pattern and Ca2+-induced slow myosin pattern in primary skeletal muscle culture.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
27 citing papers in PubMed, 83 citations in OpenAlex.
- The RyR1 P3528S Substitution Alters Mouse Skeletal Muscle Contractile Properties and RyR1 Ion Channel Gating.International journal of molecular sciences · 2023Article
- Using Vertebrate Stem and Progenitor Cells for Cellular Agriculture, State-of-the-Art, Challenges, and Future Perspectives.Biomolecules · 2022Review
- Metabolic Networks Influencing Skeletal Muscle Fiber Composition.Frontiers in cell and developmental biology · 2018Review
- Skeletal Muscle-Specific Overexpression of PGC-1α Induces Fiber-Type Conversion through Enhanced Mitochondrial Respiration and Fatty Acid Oxidation in Mice and Pigs.International journal of biological sciences · 2017Article
- Myosin Heavy Chain Expression Can Vary over the Length of Jaw and Leg Muscles.Cells, tissues, organs · 2016Article
- Extended 2D myotube culture recapitulates postnatal fibre type plasticity.BMC cell biology · 2015Article
- Article
- CaMKII content affects contractile, but not mitochondrial, characteristics in regenerating skeletal muscle.BMC physiology · 2014Article
- Calcineurin-NFAT Signaling and Neurotrophins Control Transformation of Myosin Heavy Chain Isoforms in Rat Soleus Muscle in Response to Aerobic Treadmill Training.Journal of sports science & medicine · 2014Article
- A simplified but robust method for the isolation of avian and mammalian muscle satellite cells.BMC cell biology · 2012Article
- Inverse regulation of the cytosolic Ca²⁺ buffer parvalbumin and mitochondrial volume in muscle cells via SIRT1/PGC-1α axis.PloS one · 2012Article
- Extracellular signal-regulated kinase 1/2-mediated phosphorylation of p300 enhances myosin heavy chain I/beta gene expression via acetylation of nuclear factor of activated T cells c1.Nucleic acids research · 2011Article
- The Ca(V) 1.2 Ca(2+) channel is expressed in sarcolemma of type I and IIa myofibers of adult skeletal muscle.Muscle & nerve · 2007Article
- Calcineurin A and CaMKIV transactivate PGC-1alpha promoter, but differentially regulate cytochrome c promoter in rat skeletal muscle.Pflugers Archiv : European journal of physiology · 2007Article
- A quantitative study of bioenergetics in skeletal muscle lacking carbonic anhydrase III using 31P magnetic resonance spectroscopy.Proceedings of the National Academy of Sciences of the United States of America · 2007Article
- RyR isoforms and fibre type-specific expression of proteins controlling intracellular calcium concentration in skeletal muscles.Journal of muscle research and cell motility · 2006Review
- Signaling pathways in activity-dependent fiber type plasticity in adult skeletal muscle.Journal of muscle research and cell motility · 2005Review
- Calcineurin is not involved in some mitochondrial enzyme adaptations to endurance exercise training in rat skeletal muscle.European journal of applied physiology · 2003Article
- Fast-to-slow transformation and nuclear import/export kinetics of the transcription factor NFATc1 during electrostimulation of rabbit muscle cells in culture.The Journal of physiology · 2002Article
- Activity-dependent nuclear translocation and intranuclear distribution of NFATc in adult skeletal muscle fibers.The Journal of cell biology · 2001Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A primary muscle cell culture derived from newborn rabbit muscle and growing on microcarriers in suspension was established. When cultured for several weeks, the myotubes in this model develop the completely adult pattern of fast myosin light and heavy chains. When Ca2+ ionophore is added to the culture medium on day 11, raising intracellular [Ca2+] about 10-fold, the myotubes develop to exhibit properties of an adult slow muscle by day 30, expressing slow myosin light as well as heavy chains, elevated citrate synthase, and reduced lactate dehydrogenase. The remarkable plasticity of these myotubes becomes apparent, when 8 days after withdrawal of the ionophore a marked slow-to-fast transition, as judged from the expression of isomyosins and metabolic enzymes, occurs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.