ArticleMammalian genome : official journal of the International Mammalian Genome Society1997
Isolation of candidate hybrid sterility 1 genes by cDNA selection in a 1.1 megabase pair region on mouse chromosome 17.
Article in Mammalian genome : official journal of the International Mammalian Genome Society, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 40 citations in OpenAlex.
- Different complex regulatory phenotypes underlie hybrid male sterility in divergent rodent crosses.Genetics · 2025Article
- Different complex regulatory phenotypes underlie hybrid male sterility in divergent rodent crosses.bioRxiv : the preprint server for biology · 2024Article
- Genic and chromosomal components of Prdm9-driven hybrid male sterility in mice (Mus musculus).Genetics · 2022Article
- Prdm9 Intersubspecific Interactions in Hybrid Male Sterility of House Mouse.Molecular biology and evolution · 2020Article
- Genomic Structure ofGenetics · 2019Article
- ZFP91 zinc finger protein expression pattern in normal tissues and cancers.Oncology letters · 2019Article
- Modulation ofeLife · 2018Article
- Gene Regulation and Speciation.Trends in genetics : TIG · 2017Review
- Mechanistic basis of infertility of mouse intersubspecific hybrids.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- Polymorphism in hybrid male sterility in wild-derived Mus musculus musculus strains on proximal chromosome 17.Mammalian genome : official journal of the International Mammalian Genome Society · 2009Article
- Mouse consomic strains: exploiting genetic divergence between Mus m. musculus and Mus m. domesticus subspecies.Genome research · 2008Article
- Article
- Article
- Signatures of reproductive isolation in patterns of single nucleotide diversity across inbred strains of mice.Genetics · 2005Article
- Epistasis underlying female sterility detected in hybrid breakdown in a Japonica-Indica cross of rice (Oryza sativa L.).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2005Article
- Loci affecting male fertility in hybrids between Mus macedonicus and C57BL/6.Mammalian genome : official journal of the International Mammalian Genome Society · 2004Article
- Genetic analysis of X-linked hybrid sterility in the house mouse.Mammalian genome : official journal of the International Mammalian Genome Society · 2004Article
- Hybrid breakdown caused by substitution of the X chromosome between two mouse subspecies.Genetics · 2004Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 5 institutions in 4 countries.
Funding
Abstract
The Hybrid sterility 1 (Hst1) gene causes male infertility in crosses between certain inbred strains of the laboratory and wild mouse, Mus musculus. To identify the causative gene, we have searched YAC clones encompassing the Hst1 region for testis-expressed sequences, using the cDNA selection method. We isolated 12 non-overlapping cDNA clones, sequenced them, and placed them on a physical map based on the analysis of YAC clones and total genomic DNA. The cDNA clones map to ten loci. Three cDNA sequences correspond to the proteasome subunit C5 (locus Psmb1), ornithine decarboxylase (Odc-rs15), and penta-zinc finger (Zfp91-rs1) transcripts. Three of the ten testis-expressed loci described in this report (D17Ph4e, Psmb1, and Zfp91-rs1) co-segregate with all Hst1 recombinants and, together with the Tbp gene, are therefore potential candidates for the Hst1 gene. The presented physical and genetic mapping data indicate there are no gross rearrangements distinguishing the Hst1(f) and Hst1(s) alleles.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.