ArticleAmerican journal of human genetics1997
Genetic localization of a newly recognized autosomal dominant limb-girdle muscular dystrophy with cardiac involvement (LGMD1B) to chromosome 1q11-21.
Article in American journal of human genetics, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00138931 (Genetic Studies of Patients and Their Families With Inherited Cardiovascular and Neuromuscular Diseases.), which is not on this map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Genetic Studies of Patients and Their Families With Inherited Cardiovascular and Neuromuscular Diseases.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 135 citations in OpenAlex.
- Meta-analysis of clinical characteristics of 299 carriers of LMNA gene mutations: do lamin A/C mutations portend a high risk of sudden death?Journal of molecular medicine (Berlin, Germany) · 2005Pooled it
- Role ofBiomolecules · 2021Article
- Need for NADCells · 2020Review
- The Cutting Edge: The Role of mTOR Signaling in Laminopathies.International journal of molecular sciences · 2019Review
- The Pathogenesis and Therapies of Striated Muscle Laminopathies.Frontiers in physiology · 2018Review
- Clinical phenotype, muscle MRI and muscle pathology of LGMD1F.Journal of neurology · 2013Article
- A new locus on 3p23-p25 for an autosomal-dominant limb-girdle muscular dystrophy, LGMD1H.European journal of human genetics : EJHG · 2010Article
- A new evidence for the maintenance of the sarcoglycan complex in muscle sarcolemma in spite of the primary absence of delta-SG protein.Journal of molecular medicine (Berlin, Germany) · 2007Article
- Differential expression profiling between the relative normal and dystrophic muscle tissues from the same LGMD patient.Journal of translational medicine · 2006Article
- Respiratory involvement in inherited primary muscle conditions.Journal of neurology, neurosurgery, and psychiatry · 2006Review
- A new LMNA mutation causing limb girdle muscular dystrophy 1B.Journal of neurology · 2005Article
- [Limb girdle muscular dystrophies].Der Nervenarzt · 2004Review
- myotilin Mutation found in second pedigree with LGMD1A.American journal of human genetics · 2002Article
- Cardiovascular Complications of Neuromuscular Disorders.Current treatment options in cardiovascular medicine · 2002Article
- Genomic organization of Tropomodulins 2 and 4 and unusual intergenic and intraexonic splicing of YL-1 and Tropomodulin 4.BMC genomics · 2001Article
- A cross section of autosomal recessive limb-girdle muscular dystrophies in 38 families.Journal of medical genetics · 2000Article
- Identification of a new autosomal dominant limb-girdle muscular dystrophy locus on chromosome 7.American journal of human genetics · 1999Article
- A novel Alu-like element rearranged in the dystrophin gene causes a splicing mutation in a family with X-linked dilated cardiomyopathy.American journal of human genetics · 1998Article
- A gene for autosomal recessive limb-girdle muscular dystrophy in Manitoba Hutterites maps to chromosome region 9q31-q33: evidence for another limb-girdle muscular dystrophy locus.American journal of human genetics · 1998Article
- Assignment of the tibial muscular dystrophy locus to chromosome 2q31.American journal of human genetics · 1998Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Limb-girdle muscular dystrophy (LGMD) constitutes a clinically and genetically heterogeneous group of myogenic disorders with a limb-girdle distribution of weakness. One autosomal dominant family, LGMD1A, has been linked to chromosome 5q, whereas in other autosomal dominant families linkage to this chromosome has been excluded. We studied 58 members of three families with a newly recognized autosomal dominantly inherited LGMD with cardiac involvement. A search with highly polymorphic microsatellite markers was carried out. The gene for this newly recognized dominant form of LGMD was located on chromosome 1q11-21, with a combined maximum two-point LOD score >12 at theta = 0.
Indexed as
Identifiers
9106535PMC1712459W1582562385What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.