ArticleProceedings of the National Academy of Sciences of the United States of America1997
Voltage-dependent gating characteristics of the K+ channel KAT1 depend on the N and C termini.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 55 citations in OpenAlex.
- OsKAT1 is a short Shaker potassium channel involved in root-to-shoot potassium translocation and contributes to rice grain yield.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- A charged existence: A century of transmembrane ion transport in plants.Plant physiology · 2024Review
- A Cyclic Nucleotide-Gated Channel, HvCNGC2-3, Is Activated by the Co-Presence of Na⁺ and K⁺ and Permeable to Na⁺ and K⁺ Non-Selectively.Plants (Basel, Switzerland) · 2018Article
- Fusicoccin Activates KAT1 Channels by Stabilizing Their Interaction with 14-3-3 Proteins.The Plant cell · 2017Article
- The function of the two-pore channel TPC1 depends on dimerization of its carboxy-terminal helix.Cellular and molecular life sciences : CMLS · 2016Article
- S-type Anion Channels SLAC1 and SLAH3 Function as Essential Negative Regulators of Inward K+ Channels and Stomatal Opening in Arabidopsis.The Plant cell · 2016Article
- The Arabidopsis AtPP2CA Protein Phosphatase Inhibits the GORK K+ Efflux Channel and Exerts a Dominant Suppressive Effect on Phosphomimetic-activating Mutations.The Journal of biological chemistry · 2016Article
- Involvement of the S4-S5 linker and the C-linker domain regions to voltage-gating in plant Shaker channels: comparison with animal HCN and Kv channels.Plant signaling & behavior · 2014Review
- Cytoplasmic domains and voltage-dependent potassium channel gating.Frontiers in pharmacology · 2012Article
- Preferential KAT1-KAT2 heteromerization determines inward K+ current properties in Arabidopsis guard cells.The Journal of biological chemistry · 2010Article
- The role of the C-terminus for functional heteromerization of the plant channel KDC1.Biophysical journal · 2009Article
- 30-year progress of membrane transport in plants.Planta · 2006Review
- Properties of shaker-type potassium channels in higher plants.The Journal of membrane biology · 2006Review
- Assembly of plant Shaker-like K(out) channels requires two distinct sites of the channel alpha-subunit.Biophysical journal · 2004Article
- The roles of intracellular regions in the activation of voltage-dependent potassium channels.European biophysics journal : EBJ · 2004Review
- The Arabidopsis salt overly sensitive 4 mutants uncover a critical role for vitamin B6 in plant salt tolerance.The Plant cell · 2002Article
- Functional characterization of the C-terminus of the human ether-à-go-go-related gene K(+) channel (HERG).The Journal of physiology · 2001Article
- The pore of plant K(+) channels is involved in voltage and pH sensing: domain-swapping between different K(+) channel alpha-subunits.The Plant cell · 2001Article
- Differential effects of amino-terminal distal and proximal domains in the regulation of human erg K(+) channel gating.Biophysical journal · 2000Article
- A shaker-like K(+) channel with weak rectification is expressed in both source and sink phloem tissues of Arabidopsis.The Plant cell · 2000Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
We studied how the C and N termini of the plant K+ channel KAT1 influence the voltage-dependent gating behavior by generating C- and N-terminal deletion mutants. Functional expression was observed only when C-terminal deletions were downstream of the putative cyclic nucleotide binding site. Treatments of oocytes expressing KAT1 channels with anticytoskeletal agents indicated that intact microtubules are important for functional expression. C-terminal deletions altered the voltage sensitivity of the KAT1 channel with greater deletions resulting in smaller equivalent charge movements. In contrast, a deletion in the N terminus (delta20-34) shifted the half-activation voltage by approximately -65 mV without markedly affecting the number of equivalent charges. The results reveal novel roles of the N and C termini in regulation of the voltage-dependent gating of KAT1.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.