ArticleThe American journal of pathology1997
Differential pathogenesis of lethal mousepox in congenic DBA/2 mice implicates natural killer cell receptor NKR-P1 in necrotizing hepatitis and the fifth component of complement in recruitment of circulating leukocytes to spleen.
Article in The American journal of pathology, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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Who cites it
15 citing papers in PubMed, 28 citations in OpenAlex.
- The Hemagglutinin Stem-Binding Monoclonal Antibody VIS410 Controls Influenza Virus-Induced Acute Respiratory Distress Syndrome.Antimicrobial agents and chemotherapy · 2016Article
- Thy1+ NK [corrected] cells from vaccinia virus-primed mice confer protection against vaccinia virus challenge in the absence of adaptive lymphocytes.PLoS pathogens · 2011Article
- Surviving mousepox infection requires the complement system.PLoS pathogens · 2008Article
- A role for NKG2D in NK cell-mediated resistance to poxvirus disease.PLoS pathogens · 2008Article
- Induction of natural killer cell responses by ectromelia virus controls infection.Journal of virology · 2007Article
- The natural killer complex regulates severe malarial pathogenesis and influences acquired immune responses to Plasmodium berghei ANKA.Infection and immunity · 2005Article
- Poxvirus tropism.Nature reviews. Microbiology · 2005Review
- Natural killer cell immune responses.Immunologic research · 2005Review
- Immune functions encoded by the natural killer gene complex.Nature reviews. Immunology · 2003Review
- Recognition of a virus-encoded ligand by a natural killer cell activation receptor.Proceedings of the National Academy of Sciences of the United States of America · 2002Article
- Genetic control of neuroadapted sindbis virus replication in female mice maps to chromosome 2 and associates with paralysis and mortality.Journal of virology · 2001Article
- Enhanced resistance in STAT6-deficient mice to infection with ectromelia virus.Proceedings of the National Academy of Sciences of the United States of America · 2001Article
- Differential susceptibility to hepatic inflammation and proliferation in AXB recombinant inbred mice chronically infected with Helicobacter hepaticus.The American journal of pathology · 1999Article
- Identification of nitric oxide synthase 2 as an innate resistance locus against ectromelia virus infection.Journal of virology · 1998Article
- Natural pathogens of laboratory mice, rats, and rabbits and their effects on research.Clinical microbiology reviews · 1998Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Innate resistance of C57BL/6 (B6) mice to lethal mousepox is controlled by multiple genes. Previously, four resistance genes were localized to specific subchromosomal regions and transferred onto a susceptible DBA/2 (D2) background by serial backcrossing and intercrossing to produce congenic strains. Intraperitoneally inoculated ectromelia virus was uniformly lethal and achieved similar titers in B6 and D2 mice but elicited differential responses in liver, spleen, and circulating blood leukocytes. The distribution of these response phenotypes in congenic strains linked control of phenotypes with specific subchromosomal regions. D2.R1 mice, which carried a differential segment of chromosome 6, exhibited a B6 liver response and intermediate spleen and circulating leukocyte responses. D2.R2 and D2.R4 mice, which carried differential segments of chromosomes 2 and 1, respectively, exhibited a D2 liver response, a B6 spleen response, and an intermediate circulating leukocyte response. The localization of control of liver response phenotypes to chromosome 6 implicates cells that express natural killer (NK) cell receptor NKR-P1 alloantigens. The localization of control of spleen and circulating leukocyte responses to chromosomes 1, 2, and 6 implicates NK cells, the fifth component of complement, and a gene near the selectin gene complex in recruitment of circulating leukocytes to spleen.
Indexed as
Identifiers
9094996PMC1858154W282543996What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.