ArticleJournal of virology1997
Retrovirus-like end processing of the tobacco Tnt1 retrotransposon linear intermediates of replication.
Article in Journal of virology, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed.
- Agrobacterium-mediated Tnt1 mutagenesis of moss protonemal filaments and generation of stable mutants with impaired gametophyte.Molecular genetics and genomics : MGG · 2019Article
- Structural Diversity of a Novel LTR Retrotransposon, RTPOSON, in the Genus Oryza.Evolutionary bioinformatics online · 2016Article
- How a retrotransposon exploits the plant's heat stress response for its activation.PLoS genetics · 2014Article
- An siRNA pathway prevents transgenerational retrotransposition in plants subjected to stress.Nature · 2011Article
- Invasion of the Arabidopsis genome by the tobacco retrotransposon Tnt1 is controlled by reversible transcriptional gene silencing.Plant physiology · 2008Article
- The protease and reverse transcriptase of the tobacco LTR retrotransposon Tnt1 are enzymatically active when expressed in Escherichia coli.Plant molecular biology · 2001Article
- Silencing of retrotransposons in arabidopsis and reactivation by the ddm1 mutation.The Plant cell · 2000Article
- In vivo Ty1 reverse transcription can generate replication intermediates with untidy ends.Journal of virology · 1998Article
- Replication errors during in vivo Ty1 transposition are linked to heterogeneous RNase H cleavage sites.Molecular and cellular biology · 1998Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The tobacco retrotransposon Tnt1 can transpose through an RNA intermediate in the heterologous host Arabidopsis thaliana. We report here the identification and characterization of extrachromosomal linear and circular DNA forms of Tnt1 in this heterologous host. Our results demonstrate that Tnt1 linear intermediates possess two extra base pairs at each end compared with Tnt1's integrated forms. Prior to integration into the host genome, the two terminal nucleotides at the 3' end of these linear intermediates are removed, as in the case of the yeast Ty3 retrotransposon and of retroviruses. Our data, together with those from recent studies of Ty3, reinforce the idea that 3' dinucleotide cleavage is not restricted to retroviral integrases and is probably a feature shared by many different retrotransposons' enzymes.
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Registered trials
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