ArticleBiophysical journal1997
Spontaneous transfer of monoacyl amphiphiles between lipid and protein surfaces.
Article in Biophysical journal, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 82 citations in OpenAlex.
- VLDL lipolysis products increase VLDL fluidity and convert apolipoprotein E4 into a more expanded conformation.Journal of lipid research · 2010Trial
- Fatty acid uptake inFrontiers in cellular and infection microbiology · 2022Review
- Fatty acid metabolism and acyl-CoA synthetases in theWorld journal of hepatology · 2021Review
- Structure and Dynamics of Oxidized Lipoproteins In Vivo: Roles of High-Density Lipoprotein.Biomedicines · 2021Review
- Advances in fatty acids nutrition in dairy cows: from gut to cells and effects on performance.Journal of animal science and biotechnology · 2020Review
- Transfer and Enzyme-Mediated Metabolism of Oxidized Phosphatidylcholine and Lysophosphatidylcholine between Low- and High-Density Lipoproteins.Antioxidants (Basel, Switzerland) · 2020Article
- Commentary on SSO and other putative inhibitors of FA transport across membranes by CD36 disrupt intracellular metabolism, but do not affect fatty acid translocation.Journal of lipid research · 2020Article
- Lipid Droplets Mediate Salt Stress Tolerance inPlant physiology · 2019Article
- Progress in synthesizing protocells.Experimental biology and medicine (Maywood, N.J.) · 2019Review
- Effect of Acyl Chain Length on the Rate of Phospholipid Flip-Flop and Intermembrane Transfer.The Journal of membrane biology · 2018Article
- Native and Reconstituted Plasma Lipoproteins in Nanomedicine: Physicochemical Determinants of Nanoparticle Structure, Stability, and Metabolism.Methodist DeBakey cardiovascular journal · 2016Review
- Lipid-free antigen B subunits from echinococcus granulosus: oligomerization, ligand binding, and membrane interaction properties.PLoS neglected tropical diseases · 2015Article
- Commentary on fatty acid wars: the diffusionists versus the translocatists.Arteriosclerosis, thrombosis, and vascular biology · 2014Article
- Direct interaction between EgFABP1, a fatty acid binding protein from Echinococcus granulosus, and phospholipid membranes.PLoS neglected tropical diseases · 2012Article
- Exogenous ether lipids predominantly target mitochondria.PloS one · 2012Article
- Human lysophosphatidylcholine acyltransferases 1 and 2 are located in lipid droplets where they catalyze the formation of phosphatidylcholine.The Journal of biological chemistry · 2011Article
- Kinetics of stearic acid transfer between human serum albumin and sterically stabilized liposomes.European biophysics journal : EBJ · 2010Article
- Spontaneous transfer of stearic acids between human serum albumin and PEG:2000-grafted DPPC membranes.European biophysics journal : EBJ · 2010Article
- Fatty acid transfer from Yarrowia lipolytica sterol carrier protein 2 to phospholipid membranes.Biophysical journal · 2009Article
- Effect of bilayer phospholipid composition and curvature on ligand transfer by the alpha-tocopherol transfer protein.Lipids · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
The kinetics of transfer of natural and fluorescent nonesterified fatty acids (NEFA) and lysolecithins (lysoPC) from phospholipid and protein surfaces were measured. The kinetics of transfer of 12-(1-pyrenyl)dodecanoic acid, from liquid crystalline and gel phase single unilamellar phospholipid vesicles, very low, low, and high density lipoproteins, human serum albumin, and rat liver fatty acid-binding protein, were first-order and characterized by similar rate constants. The halftimes (t1/2) of NEFA transfer from lipids and proteins were dependent on the acyl chain structure according to log t1/2 = -0.62n + 0.59m + 12.0, where n and m, respectively, are the numbers of carbon atoms and double bonds. The structure of the donor surface had a measurable but smaller effect on transfer rates. The kinetics of NEFA and lysoPC transfer are slow relative to the lipolytic processes that liberate them. Therefore, one would predict a transient accumulation of NEFA and lysoPC during lipolysis and an attendant modulation of many metabolic processes within living cells and within the plasma compartment of blood. These data will be useful in the refinement of current models of membrane and lipoprotein function and in the selection of fluorescent NEFA analogs for studying transport in living cells.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.