ArticleLipids1997
The influence of dietary lipids on the composition and membrane fluidity of rat hepatocyte plasma membrane.
Article in Lipids, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 97 citations in OpenAlex.
- Beneficial effects of long-chain n-3 fatty acids included in an energy-restricted diet on insulin resistance in overweight and obese European young adults.Diabetologia · 2008Trial
- Single-Cell and Subcellular Analysis Using Ultrahigh Resolution 21 T MALDI FTICR Mass Spectrometry.Analytical chemistry · 2023Article
- Fatty Acids: An Insight into the Pathogenesis of Neurodegenerative Diseases and Therapeutic Potential.International journal of molecular sciences · 2022Review
- Dietary Intake and Serum Selenium Levels Influence the Outcome of HTLV-1 Infection.Biological trace element research · 2021Article
- Nanoemulsion adjuvantation strategy of tumor-associated antigen therapy rephrases mucosal and immunotherapeutic signatures following intranasal vaccination.Journal for immunotherapy of cancer · 2020Article
- Membranes as the third genetic code.Molecular biology reports · 2020Review
- Deriving Lipid Classification Based on Molecular Formulas.Metabolites · 2020Article
- Characterizing the Natural History of Acute Radiation Syndrome of the Gastrointestinal Tract: Combining High Mass and Spatial Resolution Using MALDI-FTICR-MSI.Health physics · 2019Article
- Palmitic Acid: Physiological Role, Metabolism and Nutritional Implications.Frontiers in physiology · 2017Review
- Skeletal Muscle Mitochondrial Bioenergetics and Morphology in High Fat Diet Induced Obesity and Insulin Resistance: Focus on Dietary Fat Source.Frontiers in physiology · 2015Review
- Polyunsaturated fatty acids modify expression of TGF-β in a co-culture model ultilising human colorectal cells and human peripheral blood mononuclear cells exposed toEuropean journal of lipid science and technology : EJLST · 2014Article
- Relationships between changes in leptin and insulin resistance levels in obese individuals following weight loss.The Kaohsiung journal of medical sciences · 2013Article
- Saturated fatty acids induce c-Src clustering within membrane subdomains, leading to JNK activation.Cell · 2011Article
- The Bi-Directional Relationship between Periodontal Disease and Hyperlipidemia.European journal of dentistry · 2008Article
- Metabolic syndrome: effects of n-3 PUFAs on a model of dyslipidemia, insulin resistance and adiposity.Lipids · 2007Article
- Dietary alpha-linolenic acid increases brain but not heart and liver docosahexaenoic acid levels.Lipids · 2005Article
- Cell-cycle arrest in Jurkat leukaemic cells: a possible role for docosahexaenoic acid.The Biochemical journal · 2003Article
- Effect of dietary lipid (soybean lecithin and triacylglycerol) on hepatic F-actin microfilaments in cyclosporine A-treated rats: image analysis by confocal laser scanning microscopy.Digestive diseases and sciences · 2000Article
- Membrane changes in rat erythrocyte ghosts on ghee feeding.Molecular and cellular biochemistry · 2000Article
- Effect of dietary lipids on hepatic Na+,K(+)-ATPase in cyclosporine A-treated rats: immunocytochemical analysis of alpha1 subunit by confocal laser scanning microscopy imaging.Digestive diseases and sciences · 1999Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Weanling male Wistar rats were fed for five weeks on standard rat chow (23 g fat/kg diet) or one of four synthetic diets with butterfat, coconut oil, corn oil, or fish oil as the main lipid source (100 g fat/kg diet). In all diets, 10% of the fat was provided as corn oil to prevent essential fatty acid deficiency. Significant differences were observed in the saturated, monounsaturated, and polyunsaturated fatty acid composition, and in the ratio of cholesterol to phospholipid, in the hepatocyte membranes. The fluidity of hepatocyte plasma membranes was assessed using the fluorescence recovery after photobleaching technique and steady-state fluorescence anisotropy of diphenylhexatriene. No significant differences were found in the fluidity of plasma membranes between animals on the different fat diets, despite diet-induced changes in their fatty acid composition. However, the proportion of lipid free to diffuse in the plasma membrane varied with diet, being significantly greater (P < 0.05) in animals fed chow (63.7%), coconut oil (61.5%), and butterfat (57.6%) diets than in those fed the corn oil (47.3%) diet. Animals fed fish oil showed an intermediate (50.0%) proportion of lipid free to diffuse. The data support the hypothesis that dietary lipids can change both the chemical composition and lateral organization (lipid domain structure) of rat hepatocyte plasma membranes.
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