ReviewHistochemistry and cell biology1996
Antigen retrieval, signal amplification and intensification in immunohistochemistry.
Review in Histochemistry and cell biology, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed.
- Heat-induced antigen retrieval by using Tris-EDTA solution destroys nuclear structure in certain tissues.Biochemistry and biophysics reports · 2026Article
- Cell-cell communication: new insights and clinical implications.Signal transduction and targeted therapy · 2024Review
- Loss of Human Epidermal Receptor 2 Expression in Formalin-Fixed Paraffin-Embedded Breast Cancer Samples and the Rescuing Effect of Enhanced Antigen Retrieval and Signal Amplification.Life (Basel, Switzerland) · 2023Article
- Increasing reproducibility in preclinical stroke research: the correlation of immunofluorescence intensity measurements and Western blot analyses strongly depends on antibody clonality and tissue pre-treatment in a mouse model of focal cerebral ischemia.Frontiers in cellular neuroscience · 2023Article
- Strategies for monitoring cell-cell interactions.Nature chemical biology · 2021Review
- Antigen retrieval pre-treatment causes a different expression pattern of Cav3.2 in rat and mouse spinal dorsal horn.European journal of histochemistry : EJH · 2019Article
- Article
- Investigating the Cellular and Metabolic Responses of World-Class Canoeists Training: A Sportomics Approach.Nutrients · 2016Article
- Intrahepatic distribution of hepatitis B virus antigens in patients with and without hepatocellular carcinoma.World journal of gastroenterology · 2016Article
- The role of histopathology in forensic practice: an overview.Forensic science, medicine, and pathology · 2014Review
- Immunofluorescent localization of the Rab-GAP protein TBC1D4 (AS160) in mouse kidney.Histochemistry and cell biology · 2012Article
- The burn wound inflammatory response is influenced by midazolam.Inflammation · 2012Article
- Article
- Nanobarcoding: detecting nanoparticles in biological samples using in situ polymerase chain reaction.International journal of nanomedicine · 2012Article
- Characterization of organics consistent with β-chitin preserved in the Late Eocene cuttlefish Mississaepia mississippiensis.PloS one · 2011Article
- Connexins in vascular physiology and pathology.Antioxidants & redox signaling · 2009Review
- Immunohistochemical markers for quantitative studies of neurons and glia in human neocortex.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2008Article
- Low level of cyclin D1 protein expression in thyroid microcarcinomas from an autopsy series.Endocrine · 2005Article
- A simple and reliable pretreatment protocol facilitates fluorescent in situ hybridisation on tissue microarrays of paraffin wax embedded tumour samples.Molecular pathology : MP · 2003Article
- Strategies for signal amplification in nucleic acid detection.Molecular biotechnology · 2001Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this overview we emphasize new methods of improving immunohistochemical results in formaldehyde-fixed tissue samples. The benefit of heat-induced antigen retrieval in demasking of concealed epitopes is demonstrated. We provide guidance on the influence of heat-induced antigen retrieval in commonly applied monoclonal and polyclonal antibodies. Moreover, we show the promising methods of signal amplification using biotinylated tyramine and signal intensification of diaminobenzidine reaction products by metallic ions.
Indexed as
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.