ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience1997
Rapid exocytosis in single chromaffin cells recorded from mouse adrenal slices.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.
What it found
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Who cites it
54 citing papers in PubMed, 1 citations in OpenAlex.
- Calcium Imaging and Analysis in Beta Cells in Acute Mouse Pancreas Tissue Slices.Methods in molecular biology (Clifton, N.J.) · 2025Article
- Cellular mechanisms underlying pituitary adenylate cyclase activating polypeptide-stimulated secretion in the adrenal medulla.Biochemical Society transactions · 2024Review
- PACAP and acetylcholine cause distinct Ca2+ signals and secretory responses in chromaffin cells.The Journal of general physiology · 2023Article
- A NovelFrontiers in physiology · 2019Article
- How does the stimulus define exocytosis in adrenal chromaffin cells?Pflugers Archiv : European journal of physiology · 2018Review
- v-SNARE function in chromaffin cells.Pflugers Archiv : European journal of physiology · 2018Review
- Explicit Theoretical Analysis of How the Rate of Exocytosis Depends on Local Control by CaComputational and mathematical methods in medicine · 2018Article
- Cell polarity defines three distinct domains in pancreatic β-cells.Journal of cell science · 2017Article
- Article
- Sustained Exocytosis after Action Potential-Like Stimulation at Low Frequencies in Mouse Chromaffin Cells Depends on a Dynamin-Dependent Fast Endocytotic Process.Frontiers in cellular neuroscience · 2016Article
- Identification of a Munc13-sensitive step in chromaffin cell large dense-core vesicle exocytosis.eLife · 2015Article
- Testing pancreatic islet function at the single cell level by calcium influx with associated marker expression.PloS one · 2015Article
- Insulin secretion from beta cells in intact mouse islets is targeted towards the vasculature.Diabetologia · 2014Article
- Exocytotic dynamics in human chromaffin cells: experiments and modeling.Journal of computational neuroscience · 2013Article
- Article
- Glucose-stimulated calcium dynamics in islets of Langerhans in acute mouse pancreas tissue slices.PloS one · 2013Article
- On depolarization-evoked exocytosis as a function of calcium entry: possibilities and pitfalls.Biophysical journal · 2011Article
- Distinguishing splanchnic nerve and chromaffin cell stimulation in mouse adrenal slices with fast-scan cyclic voltammetry.American journal of physiology. Cell physiology · 2011Article
- Article
- Association of SNAREs and calcium channels with the borders of cytoskeletal cages organizes the secretory machinery in chromaffin cells.Cellular and molecular neurobiology · 2010Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We report here that brief depolarizations such as action potentials trigger exocytosis in thin mouse adrenal slices. The secretory rates obtained in membrane capacitance recordings from chromaffin cells in slices are faster than those observed in isolated cells. Fast exocytosis in slices is attributable to the rapid release of a small pool of vesicles. The pool recovers from depletion with a time constant of 10 sec. Recruitment of the rapidly released vesicles is strongly hindered by the fast Ca2+ chelator BAPTA and much less by the slower chelator EGTA. We suggest that these vesicles are located in close proximity to Ca2+ channels. Spatial coupling of Ca2+ entry and exocytosis may be sensitive to cell isolation and culture.
Indexed as
Identifiers
9065492PMC6573505W1543225049What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.