ArticleClinical & experimental metastasis1997
Differential expression of annexin I in human mammary ductal epithelial cells in normal and benign and malignant breast tissues.
Article in Clinical & experimental metastasis, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
44 citing papers in PubMed, 1 synthesis or guideline pooled it, 108 citations in OpenAlex.
- Annexin A1: A Bane or a Boon in Cancer? A Systematic Review.Molecules (Basel, Switzerland) · 2020Pooled it
- Proteomics of pediatric ependymomas: a review.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2021Review
- ANXA1 enhances tumor proliferation and migration by regulating epithelial-mesenchymal transition and IL-6/JAK2/STAT3 pathway in papillary thyroid carcinoma.Journal of Cancer · 2021Article
- Multi-parameter gene expression profiling of peripheral blood for early detection of hepatocellular carcinoma.World journal of gastroenterology · 2018Article
- Annexin A1 in inflammation and breast cancer: a new axis in the tumor microenvironment.Cell adhesion & migration · 2018Article
- Overcoming key biological barriers to cancer drug delivery and efficacy.Journal of controlled release : official journal of the Controlled Release Society · 2017Review
- Regulation of inflammation by members of the formyl-peptide receptor family.Journal of autoimmunity · 2017Review
- Immune-complex level of cofilin-1 in sera is associated with cancer progression and poor prognosis in pancreatic cancer.Cancer science · 2017Article
- Article
- Changes in the in vitro activity of platinum drugs when administered in two aliquots.BMC cancer · 2016Article
- Annexin A1 Preferentially Predicts Poor Prognosis of Basal-Like Breast Cancer Patients by Activating mTOR-S6 Signaling.PloS one · 2015Article
- Overexpression of ANXA1 confers independent negative prognostic impact in rectal cancers receiving concurrent chemoradiotherapy.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2014Article
- Annexin-A1 regulates microRNA-26b* and microRNA-562 to directly target NF-κB and angiogenesis in breast cancer cells.PloS one · 2014Article
- Inflammation and cancer: role of annexin A1 and FPR2/ALX in proliferation and metastasis in human laryngeal squamous cell carcinoma.PloS one · 2014Article
- Relationship between HPV and the biomarkers annexin A1 and p53 in oropharyngeal cancer.Infectious agents and cancer · 2014Article
- Article
- Proteome analysis of the effects of sorafenib on human hepatocellular carcinoma cell line HepG2.Medical oncology (Northwood, London, England) · 2012Article
- Overexpression of annexin 1 in the development and differentiation of urothelial carcinoma.The Kaohsiung journal of medical sciences · 2012Article
- Expression of FOXO1 is associated with GATA3 and Annexin-1 and predicts disease-free survival in breast cancer.American journal of cancer research · 2012Article
- Clinical significance of annexin A1 expression in breast cancer.Journal of breast cancer · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Annexins are a family of structurally related, water-soluble proteins that have calcium- and phospholipid-binding domains. Annexin I is thought to be involved in cell proliferation and differentiation and has recently been shown to be expressed on the surfaces of lymphoma cells where it acts as an endothelial cell adhesion molecule. To evaluate the expression of annexin I in relation to human breast cancer development and progression we used breast biopsy tissues. Immunohistochemical analysis of annexin I in paraffin-embedded ductal epithelial cells of various human breast tissues indicated that this annexin was not demonstrable in the ductal luminal cells of normal breast tissues (n = 11) and benign tumors (n = 10) (except for one ductal adenoma) but was generally expressed in various types of breast cancers, including noninvasive ductal carcinoma in situ (DCIS), invasive and metastatic breast tumors (n = 33). The results suggest that annexin I expression might correlate with malignant breast cancer progression but it is most likely involved at an early stage of human breast cancer development.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.