ArticleJournal of molecular neuroscience : MN1997
Molecular cloning and functional expression of a serotonin receptor from Caenorhabditis elegans.
Article in Journal of molecular neuroscience : MN, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
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Who cites it
47 citing papers in PubMed, 114 citations in OpenAlex.
- Therapeutic Effects ofInternational journal of molecular sciences · 2025Article
- Behavioral and genetic analysis of the effects of the psychedelic 2,5-dimethoxy-4-iodoamphetamine (DOI) in C. elegans.PloS one · 2025Article
- Genome-Wide Identification of 5-HT Receptor Gene Family in Razor ClamAnimals : an open access journal from MDPI · 2023Article
- Dissecting the functional organization of the C. elegans serotonergic system at whole-brain scale.Cell · 2023Article
- Article
- Dissecting the Functional Organization of thebioRxiv : the preprint server for biology · 2023Article
- The nematode serotonin-gated chloride channel MOD-1: A novel target for anthelmintic therapy.The Journal of biological chemistry · 2022Article
- Azepine-Indole Alkaloids FromFrontiers in neuroscience · 2022Article
- The Phenoxyalkyltriazine Antagonists for 5-HTInternational journal of molecular sciences · 2021Article
- Article
- Acetylcholine signaling genes are required for cocaine-stimulated egg laying in Caenorhabditis elegans.G3 (Bethesda, Md.) · 2021Article
- Different combinations of serotonin receptors regulate predatory and bacterial feeding behaviors in the nematode Pristionchus pacificus.G3 (Bethesda, Md.) · 2021Article
- Risperidone induced alterations in feeding and locomotion behavior ofCurrent research in toxicology · 2021Article
- Serotonergic modulation across sensory modalities.Journal of neurophysiology · 2020Review
- The protein kinase G orthologs, EGL-4 and PKG-2, mediate serotonin-induced paralysis ofmicroPublication biology · 2019Article
- Neurotransmitter signaling through heterotrimeric G proteins: insights from studies in C. elegans.WormBook : the online review of C. elegans biology · 2018Review
- Serotonin Drives Predatory Feeding Behavior via Synchronous Feeding Rhythms in the NematodeG3 (Bethesda, Md.) · 2017Article
- Serotonin promotes exploitation in complex environments by accelerating decision-making.BMC biology · 2016Article
- Serotonergic signalling suppresses ataxin 3 aggregation and neurotoxicity in animal models of Machado-Joseph disease.Brain : a journal of neurology · 2015Article
- Pharmacological characterization of a 5-HT1-type serotonin receptor in the red flour beetle, Tribolium castaneum.PloS one · 2013Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A cDNA encoding a serotonin receptor has been isolated from a Caenorhabditis elegans mixed stage cDNA library. The nematode serotonin receptor, designated 5HT-Ce, was permanently expressed in murine Ltk-cells, where it mediates adenylate cyclase attenuation. Sequence analysis and the pharmacological profiles demonstrate its relatedness not only to Drosophila and Lymnae 5HT receptors but also to mammalian 5HT1a receptors. The 5HT-Ce-gene does not map close to the position of any known serotonergic mutations.
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Registered trials
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