ArticleThe American journal of pathology1997
HMGI(Y) activation by chromosome 6p21 rearrangements in multilineage mesenchymal cells from pulmonary hamartoma.
Article in The American journal of pathology, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed, 88 citations in OpenAlex.
- Smooth muscle hamartoma of the lungs in a Wistar Hannover rat.Journal of toxicologic pathology · 2023Article
- Fusion of the TBL1XR1 and HMGA1 genes in splenic hemangioma with t(3;6)(q26;p21).International journal of oncology · 2016Article
- The genetic bases of uterine fibroids; a review.Journal of reproduction & infertility · 2011Article
- Article
- High-mobility group A1 proteins are overexpressed in human leukaemias.The Biochemical journal · 2003Article
- Identification of differentially expressed genes in pulmonary adenocarcinoma by using cDNA array.Oncogene · 2002Article
- High mobility group I (Y) proteins bind HIPK2, a serine-threonine kinase protein which inhibits cell growth.Oncogene · 2001Article
- The expression of HMGA genes is regulated by their 3'UTR.Oncogene · 2001Article
- Critical role of the HMGI(Y) proteins in adipocytic cell growth and differentiation.Molecular and cellular biology · 2001Article
- The HMG I proteins: dynamic roles in gene activation, development, and tumorigenesis.Immunologic research · 2001Review
- Construction of a high-resolution 2.5-Mb transcript map of the human 6p21.2-6p21.3 region immediately centromeric of the major histocompatibility complex.Genome research · 2000Article
- Misexpression of wild-type and truncated isoforms of the high-mobility group I proteins HMGI-C and HMGI(Y) in uterine leiomyomas.The American journal of pathology · 1999Article
- Rare diseases. 1. Lymphangioleiomyomatosis: clinical features, management and basic mechanisms.Thorax · 1999Review
- Physical map of human 6p21.2-6p21.3: region flanking the centromeric end of the major histocompatibility complex.Genome research · 1998Article
- Cloning and molecular characterization of part of a new gene fused to HMGIC in mesenchymal tumors.The American journal of pathology · 1998Article
- HMGI(Y) expression in human uterine leiomyomata. Involvement of another high-mobility group architectural factor in a benign neoplasm.The American journal of pathology · 1997Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The chromosome band 6p21 high-mobility group gene, HMGI(Y), encodes DNA-binding proteins with both chromatin structural and gene regulatory roles. Although HMGI(Y) expression is associated with neoplastic transformation, no oncogenic HMGI(Y) mutations have been identified. We report pulmonary chondroid hamartoma chromosome 6p21 aberrations targeting HMGI(Y). Several pulmonary chondroid hamartomas had chromosome rearrangements mapping within 100 kb of HMGI(Y), and one pulmonary chondroid hamartoma contained an intragenic fusion juxtaposing HMGI(Y) A.T book DNA-binding domains with a laminin alpha 4 chain epidermal-growth-factor-like/ zinc-finger-like motif. These findings demonstrate an oncogenic role for HMGI(Y) and for laminin chain transcriptional regulatory motifs.
Indexed as
Identifiers
9060828PMC1857887W1962434659What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.