Evidence map›Paper›PMID 9055088›Full record

ArticleGenetics1997

The geographic distribution of human Y chromosome variation.

M F Hammer, A B Spurdle, T Karafet, M R Bonner, E T Wood, A Novelletto, P Malaspina, R J Mitchell, S Horai, T Jenkins and 1 more

Abstract read
In one paragraph

Article in Genetics, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed
16.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 279 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Dispersals of the Siberian Y-chromosome haplogroup Q in Eurasia.Molecular genetics and genomics : MGG · 2018
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. A comparative phylogenetic study of genetics and folk music.Molecular genetics and genomics : MGG · 2012
    Article
  13. Article
  14. Article
  15. The Himalayas as a directional barrier to gene flow.American journal of human genetics · 2007
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 5 countries.

M F HammerLaboratory of Molecular Systematics and Evolution, University of Arizona, Tucson 85721, USA. hammer@biosci.arizona.edu
A B Spurdle
T Karafet
M R Bonner
E T Wood
A Novelletto
P Malaspina
R J Mitchell
S Horai
T Jenkins
S L Zegura
University of Arizona · USSouth African Institute for Medical Research · ZAUniversity of Rome Tor Vergata · ITLa Trobe University · AUNational Institute of Genetics · JP

Funding

Y CHROMOSOME EVOLUTION AND MODERN HUMAN ORIGINSR01GM053566 · NIGMS · UNIVERSITY OF ARIZONA · PI HAMMER, MICHAEL F · 2001 to 2004
$1.4M
Y CHROMOSOME EVOLUTION AND MODERN HUMAN ORIGINSR29GM053566 · NIGMS · UNIVERSITY OF ARIZONA · PI HAMMER, MICHAEL F · 1995 to 1999
–
NIGMS NIH HHS GM-53566
6 · The paper itself

Abstract

We examined variation on the nonrecombining portion of the human Y chromosome to investigate human evolution during the last 200,000 years. The Y-specific polymorphic sites included the Y Alu insertional polymorphism or "YAP" element (DYS287), the poly(A) tail associated with the YAP element, three point mutations in close association with the YAP insertion site, an A-G polymorphic transition (DYS271), and a tetranucleotide microsatellite (DYS19). Global variation at the five bi-allelic sites (DYS271, DYS287, and the three point mutations) gave rise to five "YAP haplotypes" in 60 populations from Africa, Europe, Asia, Australasia, and the New World (n = 1500). Combining the multi-allelic variation at the microsatellite loci (poly(A) tail and DYS19) with the YAP haplotypes resulted in a total of 27 "combination haplotypes". All five of the YAP haplotypes and 21 of the 27 combination haplotypes were found in African populations, which had greater haplotype diversity than did populations from other geographical locations. Only subsets of the five YAP haplotypes were found outside of Africa. Patterns of observed variation were compatible with a variety of hypotheses, including multiple human migrations and range expansions.

Indexed as

Genetic VariationY ChromosomeGene FrequencyHaplotypesHumansLikelihood FunctionsMalePolymorphism, Genetic

Identifiers

PMID9055088
PMCPMC1207863
OpenAlexW2157300284

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.