ArticleMolecular and cellular biochemistry1997
Fasting increases plasma membrane fatty acid-binding protein (FABP(PM)) in red skeletal muscle.
Article in Molecular and cellular biochemistry, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 73 citations in OpenAlex.
- A Critical Assessment of Fasting to Promote Metabolic Health and Longevity.Endocrine reviews · 2025Review
- Applications of Enteroendocrine Cells (EECs) Hormone: Applicability on Feed Intake and Nutrient Absorption in Chickens.Animals : an open access journal from MDPI · 2023Review
- Review
- Effect of heat stress on protein utilization and nutrient transporters in meat-type chickens.International journal of biometeorology · 2017Article
- PPAR-α, a lipid-sensing transcription factor, regulates blood-brain barrier efflux transporter expression.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2017Article
- Cellular mechanisms regulating fuel metabolism in mammals: role of adipose tissue and lipids during prolonged food deprivation.Metabolism: clinical and experimental · 2013Review
- Metabolic syndrome and insulin resistance: underlying causes and modification by exercise training.Comprehensive Physiology · 2013 · on this mapReview
- Contractions but not AICAR increase FABPpm content in rat muscle sarcolemma.Molecular and cellular biochemistry · 2009Article
- Intramuscular lipid metabolism, insulin action, and obesity.IUBMB life · 2009Review
- The role of membrane fatty-acid transporters in regulating skeletal muscle substrate use during exercise.Sports medicine (Auckland, N.Z.) · 2008Article
- Insulin-stimulated plasma membrane association and activation of Akt2, aPKC zeta and aPKC lambda in high fat fed rodent skeletal muscle.The Journal of physiology · 2005Article
- New insights into long-chain fatty acid uptake by heart muscle: a crucial role for fatty acid translocase/CD36.The Biochemical journal · 2002Review
- Muscle palmitate uptake and binding are saturable and inhibited by antibodies to FABP(PM).Molecular and cellular biochemistry · 2000Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The present study was designed to investigate the presence of the fatty acid-binding protein (FABP(PM)) in the plasma membranes of skeletal muscles with different oxidative capacities for free fatty acid (FFA) oxidation during conditions of normal (fed) or increased (fasted) FFA utilization in the rat. Female Sprague-Dawley rats were either fed or fasted for 12, 24, or 48 h and, plasma membranes (PM) fractions from red and white skeletal muscles were isolated. Short-term fasting significantly decreased body weight by 11% and blood glucose concentration by 42% (6.6+/-0.2-3.8+/-0.4 mmol/l) and increased plasma FFA concentration by 5-fold (133+/-14-793+/-81 micromol/l). Immunoblotting of PM fractions showed that FABP(PM) protein content was 83+/-18% higher in red than in white skeletal muscle and correlated with oxidative capacity as measured by succinate dehydrogenase activity (r = 0.78, p < 0.05). Short-term fasting significantly increased FABP(PM) protein content by 60+/-8% in red skeletal muscle but no change was measured in white skeletal muscle. These results show that FABP(PM) protein content in skeletal muscle is related to oxidative potential and can be increased during a physiological condition known to be associated with an increase in FFA utilization, suggesting that cellular expression of FABP(PM) may play a role in the regulation of FFA metabolism in skeletal muscle.
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