Nonsense mutations and altered splice-site selection.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

8 citing papers in PubMed.

1. CRISPR-induced exon skipping is dependent on premature termination codon mutations.Genome biology · 2018
   Article
2. Genetics of isolated growth hormone deficiency.Journal of clinical research in pediatric endocrinology · 2010
   Review
3. Noncanonical and canonical splice sites: a novel mutation at the rare noncanonical splice-donor cut site (IVS4+1A>G) of SEDL causes variable splicing isoforms in X-linked spondyloepiphyseal dysplasia tarda.European journal of human genetics : EJHG · 2009
   Article
4. Unspliced Rous sarcoma virus genomic RNAs are translated and subjected to nonsense-mediated mRNA decay before packaging.Journal of virology · 2004
   Article
5. The human XPC DNA repair gene: arrangement, splice site information content and influence of a single nucleotide polymorphism in a splice acceptor site on alternative splicing and function.Nucleic acids research · 2002
   Article
6. A nonsense mutation in the fibrillin-1 gene of a Marfan syndrome patient induces NMD and disrupts an exonic splicing enhancer.Genes & development · 2002
   Article
7. RNA-protein interactions that regulate pre-mRNA splicing.Gene expression · 2002
   Review
8. Binary specification of nonsense codons by splicing and cytoplasmic translation.The EMBO journal · 1998
   Article

Corrections and comments

• Comment on
  Defects in RNA splicing and the consequence of shortened translational reading frames.1996

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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