Evidence map›Paper›PMID 9041415›Full record

ArticleJournal of clinical microbiology1997

Characterization of mycobacterial isolates phylogenetically related to, but different from Mycobacterium simiae.

E Tortoli, C Piersimoni, P Kirschner, A Bartoloni, C Burrini, C Lacchini, A Mantella, G Muzzi, C P Tosi, V Penati and 3 more

Open access · bronzeAbstract readCase ReportsComparative Study
In one paragraph

Article in Journal of clinical microbiology, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 52 citations in OpenAlex.

  1. Journal of clinical tuberculosis and other mycobacterial diseases · 2025
    Article
  2. Review
  3. Mycobacterium sherrisii sp. nov., a slow-growing non-chromogenic species.International journal of systematic and evolutionary microbiology · 2011
    Article
  4. Article
  5. Article
  6. Article
  7. Mycobacterium lentiflavum, a recently identified slow-growing mycobacterial species: clinical significance in immunosuppressed cancer patients and summary of reported cases of infection.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2005
    Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Human infections due to Mycobacterium lentiflavum.Journal of clinical microbiology · 2002
    Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

E TortoliLaboratory of Microbiology and Virology, Careggi Hospital, Firenze, Italy. tortoli@dada.it
C Piersimoni
P Kirschner
A Bartoloni
C Burrini
C Lacchini
A Mantella
G Muzzi
C P Tosi
V Penati
C Scarparo
M T Simonetti
E C Böttger
Azienda Ospedaliero-Universitaria Careggi · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of high-performance liquid chromatography (HPLC) revealed four previously unreported profiles within a group of mycobacteria consisting of 14 clinical isolates. These mycobacteria, whose identification by conventional tests appeared problematic, mostly resembled Mycobacterium avium complex or Mycobacterium simiae. Genetic analysis revealed, within this group, six different nucleic acid sequences in a hypervariable 16S rRNA segment, but all the isolates appeared to be phylogenetically related to M. simiae. Six isolates representing the largest of groups defined by means of genetic sequencing turned out to belong to the newly described species Mycobacterium lentiflavum. Furthermore, three such clusters precisely coincided with three of those defined by HPLC, while the three remaining clusters shared almost identical HPLC profiles. All but one strain (which, although clearly not belonging to the M. avium complex, hybridized with specific commercial DNA probes) showed high-grade resistance to the majority of antimycobacterial drugs. Three of the isolates were clinically significant according to stringent criteria. Sophisticated techniques, like genetic sequencing or HPLC, by now seem indispensable for differentiating unusual and new mycobacteria from well-established ones.

Indexed as

Bacteriological TechniquesPhylogenyAdultAgedBase SequenceChildChild, PreschoolChromatography, High Pressure LiquidDNA, BacterialFemaleHumansLipidsMaleMiddle AgedMolecular Sequence DataMycobacteriumDNA, BacterialLipidsRNA, BacterialRNA, Ribosomal, 16S

Identifiers

PMID9041415
PMCPMC229653
OpenAlexW2167578505

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.