Evidence map›Paper›PMID 9035371›Full record

ArticleVirus genes1996

Bovine herpesvirus 1 isolates contain variable copy numbers of GC-rich tandem repeats in the gI non-coding regions of their genomes.

S A Nadin-Davis, C Lutze-Wallace, X Zhong

Abstract read
PubMed Publisher
In one paragraph

Article in Virus genes, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

S A Nadin-DavisPathobiology Section, Agriculture and Agri-Food Canada, Ontario, Canada.
C Lutze-Wallace
X Zhong
Agriculture and Agri-Food Canada · CAAnimal Diseases Research Institute · TZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A polymerase chain reaction (PCR) targeted to the central portion of the bovine herpesvirus 1 (BHV1) genome, and overlapping the 3' untranslated end of the gI glycoprotein, was used to amplify BHV1 genomic sequences. PCR products generated from cell cultures infected with BHV1.1 were consistently smaller than the corresponding products from cells infected with BHV1.2. The nature of the sequence differences between these isolates within the target region was found to be a consequence of variable numbers of small GC rich repeats, particularly the sequence 5'-G(A/T)CC-3', present in the region downstream of the gI coding region. Based on these differences a modified PCR protocol which readily discriminated between several BHV1.1 and BHV1.2 strains was devised.

Indexed as

Genome, ViralRepetitive Sequences, Nucleic AcidAnimalsBase SequenceCattleCell LineCytosineDNA, ViralGene DosageGenetic VariationGuanineHerpesvirus 1, BovineMolecular Sequence DataSequence Homology, Nucleic AcidSpecies SpecificityViral Proteinsbovine herpesvirus type-1 glycoproteinsCytosineDNA, ViralGuanineViral Proteins

Identifiers

PMID9035371
OpenAlexW2044625108

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.