Evidence map›Paper›PMID 9032646›Full record

ArticleJournal of medical genetics1997

Recombinations defining centromeric and telomeric borders for the hereditary haemochromatosis locus.

R S Ajioka, P Yu, J R Gruen, C Q Edwards, L M Griffen, J P Kushner

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of medical genetics, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

R S AjiokaDivision of Hematology/Oncology, University of Utah Health Sciences Center, Salt Lake City 84132, USA.
P Yu
J R Gruen
C Q Edwards
L M Griffen
J P Kushner
University of Utah · US

Funding

HEREDITARY HEMOCHROMATOSISR01DK020630 · NIDDK · UNIVERSITY OF UTAH · PI KUSHNER, JAMES P · 1986 to 2001
$632k
SELECTION OF THE PRIMARY HEMOCHROMATOSIS GENER29DK045819 · NIDDK · YALE UNIVERSITY · PI GRUEN, JEFFREY R · 1992 to 1996
–
NIDDK NIH HHS 1R29DK45819-03NIDDK NIH HHS DK-20630
6 · The paper itself

Abstract

Hereditary haemochromatosis (HFE) is a common inherited disorder, affecting approximately five per thousand white people of northern European descent. Genetic linkage and linkage disequilibrium studies indicate that the disease locus is tightly linked to HLA-A and D6S105. Recombination between HFE and HLA class I loci is known to be rare. We report here two pedigrees in which recombinations telomeric of HLA-A occurred. These recombinant events define new centromeric and telomeric borders for the HFE locus.

Indexed as

Chromosomes, HumanRecombination, GeneticAdolescentAdultCentromereChildChromosome MappingDNAFemaleGenetic LinkageGenetic MarkersHaplotypesHemochromatosisHLA AntigensHumansIronDNAGenetic MarkersHLA AntigensIron

Identifiers

PMID9032646
PMCPMC1050843
OpenAlexW2022973481

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.