ArticleNucleic acids research1996
Cytosine-specific chemical probing of DNA using bromide and monoperoxysulfate.
Article in Nucleic acids research, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
27 citing papers in PubMed.
- i-Motif DNA molecular beacon for microRNA detection.Nucleic acids research · 2025Article
- A dynamic i-motif with a duplex stem-loop in the long terminal repeat promoter of the HIV-1 proviral genome modulates viral transcription.Nucleic acids research · 2019Article
- Systematic investigation of sequence requirements for DNA i-motif formation.Nucleic acids research · 2019Article
- Synthesis of Site-Specific Crown Ether Adducts to DNA Abasic Sites: 8-Oxo-7,8-Dihydro-2'-Deoxyguanosine and 2'-Deoxycytidine.Methods in molecular biology (Clifton, N.J.) · 2019Article
- Unusual Isothermal Hysteresis in DNA i-Motif pH Transitions: A Study of the RAD17 Promoter Sequence.Biophysical journal · 2018Article
- A biochemical and biophysical model of G-quadruplex DNA recognition by positive coactivator of transcription 4.The Journal of biological chemistry · 2017Article
- The stability of DNA intrastrand cross-links of antitumor transplatin derivative containing non-bulky methylamine ligands.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2014Article
- Base excision repair of oxidative DNA damage coupled with removal of a CAG repeat hairpin attenuates trinucleotide repeat expansion.Nucleic acids research · 2014Article
- The dynamic character of the BCL2 promoter i-motif provides a mechanism for modulation of gene expression by compounds that bind selectively to the alternative DNA hairpin structure.Journal of the American Chemical Society · 2014Article
- G-quadruplex and i-motif are mutually exclusive in ILPR double-stranded DNA.Biophysical journal · 2012Article
- Thermodynamic stability and energetics of DNA duplexes containing major intrastrand cross-links of second-generation antitumor dinuclear Pt(II) complexes.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2012Article
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- Premutation huntingtin allele adopts a non-B conformation and contains a hot spot for DNA damage.Biochemical and biophysical research communications · 2011Article
- Article
- Excursions in polynuclear platinum DNA binding.Chemical communications (Cambridge, England) · 2010Article
- Coexistence of an ILPR i-motif and a partially folded structure with comparable mechanical stability revealed at the single-molecule level.Journal of the American Chemical Society · 2010Article
- The i-motif in the bcl-2 P1 promoter forms an unexpectedly stable structure with a unique 8:5:7 loop folding pattern.Journal of the American Chemical Society · 2009Article
- Factors affecting DNA-DNA interstrand cross-links in the antiparallel 3'-3' sense: a comparison with the 5'-5' directional isomer.Chemistry (Weinheim an der Bergstrasse, Germany) · 2009Article
- The importance of negative superhelicity in inducing the formation of G-quadruplex and i-motif structures in the c-Myc promoter: implications for drug targeting and control of gene expression.Journal of medicinal chemistry · 2009Article
- Biophysical studies on the stability of DNA intrastrand cross-links of transplatin.Biophysical journal · 2008Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bromination of cytosine and formation of a piperidine-labile site are observed when two simple salts, KBr and KHSO5, are allowed to react with single-stranded oligodeoxynucleotides. Selectivity for C compared with T, G or A is typically a factor of 4 or more; selectivity for Cs in a single-stranded region such as a C-bulge is nearly a factor of 10 compared with duplex Cs. Low reactivity and little base selectivity are observed using duplex DNA, although increased concentrations of reagents lead to complete degradation of the DNA. The results suggest that these conditions for in situ generation of Br2 constitute a useful tool for examination of the exposure of a non-duplex cytosine base in folded DNA structures.
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