ArticleNucleic acids research1997
The alpha/beta fold family of proteins database and the cholinesterase gene server ESTHER.
Article in Nucleic acids research, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 49 citations in OpenAlex.
- Gallic Acid as a Non-Selective Inhibitor of α/β-Hydrolase Fold Enzymes Involved in the Inflammatory Process: The Two Sides of the Same Coin.Pharmaceutics · 2022Article
- Perspectives on the Role of Enzymatic Biocatalysis for the Degradation of Plastic PET.International journal of molecular sciences · 2021Review
- The role of thyroglobulin in thyroid hormonogenesis.Nature reviews. Endocrinology · 2019Review
- Article
- Carboxylic ester hydrolases: Classification and database derived from their primary, secondary, and tertiary structures.Protein science : a publication of the Protein Society · 2016Review
- ESTHER, the database of the α/β-hydrolase fold superfamily of proteins: tools to explore diversity of functions.Nucleic acids research · 2013Article
- Purification and characterization of organic solvent and detergent tolerant lipase from thermotolerant Bacillus sp. RN2.International journal of molecular sciences · 2010Article
- Neuroligin trafficking deficiencies arising from mutations in the alpha/beta-hydrolase fold protein family.The Journal of biological chemistry · 2010Article
- Acetylcholinesterase: from 3D structure to function.Chemico-biological interactions · 2010Article
- Structural and functional insights into Mimivirus ORFans.BMC genomics · 2007Article
- Large-scale identification of human genes implicated in epidermal barrier function.Genome biology · 2007Article
- ESTHER, the database of the alpha/beta-hydrolase fold superfamily of proteins.Nucleic acids research · 2004Article
- Acetylcholinesterase active centre and gorge conformations analysed by combinatorial mutations and enantiomeric phosphonates.The Biochemical journal · 2003Article
- A modular treatment of molecular traffic through the active site of cholinesterase.Biophysical journal · 1999Article
- EDS1, an essential component of R gene-mediated disease resistance in Arabidopsis has homology to eukaryotic lipases.Proceedings of the National Academy of Sciences of the United States of America · 1999Article
- aCHEdb: the database system for ESTHER, the alpha/beta fold family of proteins and the Cholinesterase gene server.Nucleic acids research · 1998Article
Corrections and comments
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Authors and funding
6 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
ESTHER (for esterases, alpha/betahydrolase enzyme and relatives) is a database of sequences phylogenetically related to cholinesterases. These sequences define a homogeneous group of enzymes (carboxylesterases, lipases and hormone-sensitive lipases) sharing a similar structure of a central beta-sheet surrounded by alpha-helices. Among these proteins a wide range of functions can be found (hydrolases, adhesion molecules, hormone precursors). The purpose of ESTHER is to help comparison of structures and functions of members of the family. Since the last release, new features have been added to the server. A BLAST comparison tool allows sequence homology searches within the database sequences. New sections are available: kinetics and inhibitors of cholinesterases, fasciculin-acetylcholinesterase interaction and a gene structure review. The mutation analysis compilation has been improved with three-dimensional images. A mailing list has been created.
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