ArticleProceedings of the National Academy of Sciences of the United States of America1997
Evolution of trans-splicing plant mitochondrial introns in pre-Permian times.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 69 citations in OpenAlex.
- A record-setting mitogenome in the holoparasitic plant Balanophora yakushimensis accompanied by exceptional loss of organellar DNA repair and recombination genes.BMC biology · 2025Article
- Assembly and comparative analysis of the complete mitochondrial genome of Cardiocrinum giganteum: a primitive Liliaceae group with significant scientific research value.BMC genomics · 2025Article
- Comparative Analysis ofBiology · 2023Article
- Rickettsial DNA and a trans-splicing rRNA group I intron in the unorthodox mitogenome of the fern Haplopteris ensiformis.Communications biology · 2023Article
- Numtogenesis as a mechanism for development of cancer.Seminars in cancer biology · 2017Review
- The Reverse Transcriptase/RNA Maturase Protein MatR Is Required for the Splicing of Various Group II Introns in Brassicaceae Mitochondria.The Plant cell · 2016Article
- Loss of a Trans-Splicing nad1 Intron from Geraniaceae and Transfer of the Maturase Gene matR to the Nucleus in Pelargonium.Genome biology and evolution · 2016Article
- The Oxytricha trifallax mitochondrial genome.Genome biology and evolution · 2012Article
- RNA-Mediated Epigenetic Programming of Genome Rearrangements.Annual review of genomics and human genetics · 2011Review
- Extensive loss of translational genes in the structurally dynamic mitochondrial genome of the angiosperm Silene latifolia.BMC evolutionary biology · 2010Article
- Extensive mis-splicing of a bi-partite plant mitochondrial group II intron.Nucleic acids research · 2010Article
- The complete mitochondrial genome sequence of the hornwort Megaceros aenigmaticus shows a mixed mode of conservative yet dynamic evolution in early land plant mitochondrial genomes.Journal of molecular evolution · 2009Article
- Distinctive architecture of the chloroplast genome in the chlorophycean green alga Stigeoclonium helveticum.Molecular genetics and genomics : MGG · 2006Article
- A novel additional group II intron distinguishes the mitochondrial rps3 gene in gymnosperms.Journal of molecular evolution · 2005Article
- The mitochondrial DNA of land plants: peculiarities in phylogenetic perspective.Current genetics · 2004Review
- Many independent origins of trans splicing of a plant mitochondrial group II intron.Journal of molecular evolution · 2004Article
- Horizontal gene transfer from flowering plants to Gnetum.Proceedings of the National Academy of Sciences of the United States of America · 2003Article
- The mitochondrial genome of Chara vulgaris: insights into the mitochondrial DNA architecture of the last common ancestor of green algae and land plants.The Plant cell · 2003Article
- The chloroplast and mitochondrial genome sequences of the charophyte Chaetosphaeridium globosum: insights into the timing of the events that restructured organelle DNAs within the green algal lineage that led to land plants.Proceedings of the National Academy of Sciences of the United States of America · 2002Article
- Repair of CFTR mRNA by spliceosome-mediated RNA trans-splicing.Gene therapy · 2000Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Trans-splicing in angiosperm plant mitochondria connects exons from independent RNA molecules by means of group II intron fragments. Homologues of trans-splicing introns in the angiosperm mitochondrial nad2 and nad5 genes are now identified as uninterrupted group II introns in the ferns Asplenium nidus and Marsilea drummondii. These fern introns are correctly spliced from the pre-mRNA at the sites predicted from their well-conserved secondary structures. The flanking exon sequences of the nad2 and nad5 genes in the ferns require RNA editing, including the removal of in-frame stop codons by U-to-C changes for correct expression of the genetic information. We conclude that cis-splicing introns like the ones now identified in ferns are the ancestors of trans-splicing introns in angiosperm mitochondria. Intron disruption is apparently due to a size increase of the structurally variable group II intron domain IV followed by DNA recombination in the plant mitochondrial genome.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.