The effect of parental gender on the GAA dynamic mutation in the FRDA gene.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

20 citing papers in PubMed.

1. Human pluripotent stem cell models of Friedreich's ataxia: innovations, considerations, and future perspectives.Stem cell research & therapy · 2026
   Review
2. Characteristics of tandem repeat inheritance and sympathetic nerve involvement in GAA-FGF14 ataxia.Journal of human genetics · 2024
   Article
3. The Regulation of the Disease-Causing GeneCells · 2024
   Review
4. Friedreich's Ataxia Frequency in a Large Cohort of Genetically Undetermined Ataxia Patients.Frontiers in neurology · 2021
   Article
5. MutLα heterodimers modify the molecular phenotype of Friedreich ataxia.PloS one · 2014
   Article
6. Microsatellites as targets of natural selection.Molecular biology and evolution · 2013
   Article
7. Effects of Friedreich's ataxia GAA repeats on DNA replication in mammalian cells.Nucleic acids research · 2012
   Article
8. The mismatch repair system protects against intergenerational GAA repeat instability in a Friedreich ataxia mouse model.Neurobiology of disease · 2012
   Article
9. Friedreich's ataxia induced pluripotent stem cells model intergenerational GAA⋅TTC triplet repeat instability.Cell stem cell · 2010
   Article
10. Friedreich ataxia: molecular mechanisms, redox considerations, and therapeutic opportunities.Antioxidants & redox signaling · 2010
    Review
11. Progressive GAA.TTC repeat expansion in human cell lines.PLoS genetics · 2009
    Article
12. Friedreich ataxia: the clinical picture.Journal of neurology · 2009
    Review
13. Repair of DNA double-strand breaks within the (GAA*TTC)n sequence results in frequent deletion of the triplet-repeat sequence.Nucleic acids research · 2008
    Article
14. The GAA triplet-repeat is unstable in the context of the human FXN locus and displays age-dependent expansions in cerebellum and DRG in a transgenic mouse model.Human genetics · 2007
    Article
15. A pathogenetic classification of hereditary ataxias: is the time ripe?Journal of neurology · 2004
    Review
16. Friedreich ataxia: an overview.Journal of medical genetics · 2000
    Review
17. FMR1 CGG-repeat instability in single sperm and lymphocytes of fragile-X premutation males.American journal of human genetics · 1999
    Article
18. DNA secondary structure: a common and causative factor for expansion in human disease.Proceedings of the National Academy of Sciences of the United States of America · 1999
    Review
19. Sperm DNA analysis in a Friedreich ataxia premutation carrier suggests both meiotic and mitotic expansion in the FRDA gene.Journal of medical genetics · 1998
    Article
20. Determinants of onset age in Friedreich's ataxia.Journal of neurology · 1998
    Article

Corrections and comments

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Authors and funding

9 authors.

Funding

Abstract

PubMed holds no abstract for this paper.

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