Evidence map›Paper›PMID 9011436›Full record

Trial reportDigestive diseases and sciences1996

Effects of calcisorb on fecal bile acids and fatty acids in human volunteers.

A van Faassen, A E van den Bogaard, M J Hazen, P Geerlings, R J Hermus, R A Janknegt

Abstract readClinical TrialControlled Clinical Trial
PubMed Publisher
In one paragraph

Trial report in Digestive diseases and sciences, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

A van FaassenDepartment of Urology, University Hospital Maastricht, The Netherlands.
A E van den Bogaard
M J Hazen
P Geerlings
R J Hermus
R A Janknegt
Maastricht University · NLMaastricht University Medical Centre · NLFood & Nutrition · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The intake of calcium (Ca) is negatively associated with colorectal cancer (crc) risk. The aim of this study was to investigate in a double-blind, placebo-controlled trial, the effects of the Ca-binder Calcisorb, which is given to kidney stone patients with hypercalciuria type I, on risk factors for crc risk, bile acids (BA), and long-chain fatty acids (LCFA) in fecal water. Results show that the concentration of BA and LCFA in fecal water did not change, although the urinary excretion of Ca and magnesium (Mg) and the concentration of Ca and magnesium in fecal water decreased. The daily excretion of BA and LCFA acids decreased significantly (p < 0.05) during the Calcisorb period. In conclusion, binding dietary Ca and Mg with Calcisorb from a diet with a relatively low amount of fat does not enhance the solubility of BA and LCFA in fecal water.

Indexed as

AdultBile Acids and SaltsCalciumCelluloseDouble-Blind MethodFatty AcidsFecesHumansMagnesiumMaleReference ValuesRisk FactorsBile Acids and SaltsCalciumCelluloseFatty AcidsMagnesiumphosphocellulose

Identifiers

PMID9011436
OpenAlexW2006522940

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.