ArticleUrological research1996
Ureaplasma urealyticum-induced urinary tract stones in rats.
Article in Urological research, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed, 4 citations in OpenAlex.
- The Quantitative Detection of Urogenital Mycoplasmas in Men with Urolithiasis.Pathogens (Basel, Switzerland) · 2025Article
- Occurrence of urogenital mycoplasmas in men with the common genitourinary diseases.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2021Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study investigated the possible role of Ureaplasma urealyticum, which is predominantly located in the urogenital tract, in the formation of infectious stones. A standardized Ureaplasma urealyticum broth culture isolated from a human urogenital specimen was inoculated into the renal medulla of five male rats (Rattus norvegicus L., Wistar C, weighing 170 +/- 10 g) and the same amount of culture media was used for five identical control rats. Five days after the inoculation, the rats were killed and fresh preparations from the bladders and the inoculated kidneys of both groups were prepared. At the same time biochemical and histopathological analysis of the contents of the bladders and the inoculated kidneys of both groups was performed. Crystal formation within the bladders of the inoculated rats was demonstrated and biochemical analysis of the crystals showed calcium, magnesium and phosphate, which indicated the existence of infection-induced crystals. These findings were absent in the control rats. The role of Ureaplasma in the production of urinary tract infectious stones was thus demonstrated in vivo.
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