ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience1997
Cloning, characterization, and expression of a G-protein-coupled receptor from Lymnaea stagnalis and identification of a leucokinin-like peptide, PSFHSWSamide, as its endogenous ligand.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Leucokinins: Multifunctional Neuropeptides and Hormones in Insects and Other Invertebrates.International journal of molecular sciences · 2021Review
- The Cattle Fever Tick,Frontiers in physiology · 2019Article
- Emergence of a cholecystokinin/sulfakinin signalling system in Lophotrochozoa.Scientific reports · 2018Article
- Discovery of leucokinin-like neuropeptides that modulate a specific parameter of feeding motor programs in the molluscan model,The Journal of biological chemistry · 2017Article
- Tracing the evolutionary origins of insect renal function.Nature communications · 2015Article
- Endocrine disruption in aquatic pulmonate molluscs: few evidences, many challenges.Ecotoxicology (London, England) · 2007Review
- Neuropeptides and neuropeptide receptors in the Drosophila melanogaster genome.Genome research · 2001Article
- The lymnaea cardioexcitatory peptide (LyCEP) receptor: a G-protein-coupled receptor for a novel member of the RFamide neuropeptide family.The Journal of neuroscience : the official journal of the Society for Neuroscience · 1998Article
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Authors and funding
8 authors.
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Abstract
Neuropeptides are known to be important signaling molecules in several neural systems of the pond snail Lymnaea stagnalis. Although the functions of these peptides have been studied in many neurons, the nature of the postsynaptic signal transduction is mainly unknown. The cloning and characterization of neuropeptide receptors in Lymnaea thus would be very valuable in further elucidating peptidergic pathways. Indirect evidence suggests that these neuropeptides operate via G-protein-coupled mechanisms indicating the presence of G-protein-coupled receptors as the initial postsynaptic targets. Here we describe the cloning of a neuropeptide receptor from Lymnaea and the isolation of an endogenous ligand. This peptide, PSFHSWSamide, belongs to the leucokinin family of peptides, and, thus, this Lymnaea receptor is the first example of a leucokinin-like neuropeptide receptor, representing a new subfamily of G-protein-coupled neuropeptide receptors.
Indexed as
Identifiers
9006965PMC6793731What OpenQuestion holds
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