ArticleJournal of clinical microbiology1997
Biodiversity of Pneumocystis carinii hominis: typing with different DNA regions.
Article in Journal of clinical microbiology, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Consensus Multilocus Sequence Typing Scheme forJournal of fungi (Basel, Switzerland) · 2020Review
- Multilocus sequence typing of Pneumocystis jirovecii from clinical samples: how many and which loci should be used?Journal of clinical microbiology · 2013Article
- Restriction fragment length polymorphism typing demonstrates substantial diversity among Pneumocystis jirovecii isolates.The Journal of infectious diseases · 2009Article
- Genotypic study of Pneumocystis jirovecii in human immunodeficiency virus-positive patients in Thailand.Journal of clinical microbiology · 2005Article
- Strain typing methods and molecular epidemiology of Pneumocystis pneumonia.Emerging infectious diseases · 2004Review
- Genotypic variation and stability of four variable-number tandem repeats and their suitability for discriminating strains of Mycobacterium leprae.Journal of clinical microbiology · 2004Article
- Genotypes at the internal transcribed spacers of the nuclear rRNA operon of Pneumocystis jiroveci in nonimmunosuppressed infants without severe pneumonia.Journal of clinical microbiology · 2003Article
- Pneumocystis jiroveci internal transcribed spacer types in patients colonized by the fungus and in patients with pneumocystosis from the same French geographic region.Journal of clinical microbiology · 2003Article
- Genetic diversity of Pneumocystis carinii f. sp. hominis based on variations in nucleotide sequences of internal transcribed spacers of rRNA genes.Journal of clinical microbiology · 2002Article
- Heterogeneity and compartmentalization of Pneumocystis carinii f. sp. hominis genotypes in autopsy lungs.Journal of clinical microbiology · 2001Article
- Genetic diversity of Pneumocystis carinii isolated from human immunodeficiency virus-positive patients in Turin, Italy.Journal of clinical microbiology · 2001Article
- Internal transcribed spacer regions of rRNA genes of Pneumocystis carinii from monkeys.Clinical and diagnostic laboratory immunology · 2001Article
- Rapid detection of mutations in the human-derived Pneumocystis carinii dihydropteroate synthase gene associated with sulfa resistance.Antimicrobial agents and chemotherapy · 2001Article
- Population structure of rat-derived Pneumocystis carinii in Danish wild rats.Applied and environmental microbiology · 2000Article
- Determination of copy number of rRNA genes in Pneumocystis carinii f. sp. hominis.Journal of clinical microbiology · 1998Article
- Identification of Pneumocystis carinii f. sp. hominis gene sequences in filtered air in hospital environments.Journal of clinical microbiology · 1998Article
- Update on Pneumocystis carinii f. sp. hominis typing based on nucleotide sequence variations in internal transcribed spacer regions of rRNA genes.Journal of clinical microbiology · 1998Article
- Pre-AIDS era isolates of Pneumocystis carinii f. sp. hominis: high genotype similarity with contemporary isolates.Journal of clinical microbiology · 1998Article
- Typing of Pneumocystis carinii f. sp. hominis by single-strand conformation polymorphism of four genomic regions.Journal of clinical microbiology · 1997Article
- Study of internal transcribed spacer and mitochondrial large-subunit genes of Pneumocystis carinii hominis isolated by repeated bronchoalveolar lavage from human immunodeficiency virus-infected patients during one or several episodes of pneumonia.Journal of clinical microbiology · 1997Article
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9 authors.
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Abstract
The purpose of this study was to identify the most useful gene for the detection of biodiversity of Pneumocystis carinii hominis isolates and to compare samples from French and Italian subjects. We studied 20 bronchoalveolar lavage fluid specimens from 20 human immunodeficiency virus-infected patients (10 French and 10 Italian patients) with Pneumocystis carinii pneumonia by DNA sequencing of the thymidylate synthase (TS), 5S rRNA, large-subunit mitochondrial rRNA (mt LSU rRNA), and internal transcribed spacer (ITS1 and ITS2) genes. Thirteen of the 20 sequenced samples had the prototype TS gene sequence. Fourteen of the 20 samples showed the prototype sequence of the 5S rRNA gene, and 6 had variant sequences of the 5S rRNA gene. The mt LSU rRNA gene was sequenced for 18 of the 20 samples; all sequences were different from the prototype sequence and were classified into four groups. Thirteen of the 20 ITS1 and ITS2 sequences were analyzed, and all the sequences were found to be different from the prototype sequence and were classified into 10 groups. The internal transcribed spacer regions thus appear to be the most discriminatory region of DNA for analysis of the biodiversity of P. carinii hominis isolates.
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