ArticleJournal of clinical microbiology1997
Rapid susceptibility testing of Candida albicans by flow cytometry.
Article in Journal of clinical microbiology, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- Use of image cytometry for quantification of pathogenic fungi in association with host cells.Journal of visualized experiments : JoVE · 2013Article
- Comparison of two probes for testing susceptibilities of pathogenic yeasts to voriconazole, itraconazole, and caspofungin by flow cytometry.Journal of clinical microbiology · 2005Article
- Flow cytometry susceptibility testing for the antifungal caspofungin.Journal of clinical microbiology · 2005Article
- Collaborative study of the NCCLS and flow cytometry methods for antifungal susceptibility testing of Candida albicans.Journal of clinical microbiology · 2004Article
- Flow cytometry antifungal susceptibility testing of Aspergillus fumigatus and comparison of mode of action of voriconazole vis-à-vis amphotericin B and itraconazole.Antimicrobial agents and chemotherapy · 2003Article
- Conidial viability assay for rapid susceptibility testing of Aspergillus species.Journal of clinical microbiology · 2002Article
- Antifungal susceptibility testing: practical aspects and current challenges.Clinical microbiology reviews · 2001Review
- Antifungal susceptibility testing of fluconazole by flow cytometry correlates with clinical outcome.Journal of clinical microbiology · 2001Article
- Flow cytometry antifungal susceptibility testing of pathogenic yeasts other than Candida albicans and comparison with the NCCLS broth microdilution test.Antimicrobial agents and chemotherapy · 2000Article
- Applications of flow cytometry to clinical microbiology.Clinical microbiology reviews · 2000Review
- Flow cytometric testing of susceptibilities of Mycobacterium tuberculosis isolates to ethambutol, isoniazid, and rifampin in 24 hours.Journal of clinical microbiology · 1998Article
- Characteristics and dynamics of bacterial populations during postantibiotic effect determined by flow cytometry.Antimicrobial agents and chemotherapy · 1998Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The emerging magnitude of human fungal infections has renewed interest in developing rapid and standardized methods for susceptibility testing. We demonstrated that susceptibility testing of Candida albicans can be accomplished rapidly by using flow cytometry. Test results were available within 8 to 24 h after C. albicans isolates were incubated with amphotericin B, itraconazole, and flucytosine. This is an improvement of 24 to 60 h in the time to availability of susceptibility test results compared to the time to availability of National Committee for Clinical Laboratory Standards-recommended broth macrodilution test results. In addition, the flow cytometric endpoints, mean channel fluorescence, and number of fluorescence-labeled C. albicans cells were easy to interpret for greater sensitivity and reliability. Flow cytometry provides a more accurate means of obtaining antifungal susceptibility test results.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.