ArticleMammalian genome : official journal of the International Mammalian Genome Society1996
Genetic mapping of 18S ribosomal RNA-related loci to mouse chromosomes 5, 6, 9, 12, 17, 18, 19, and X.
Article in Mammalian genome : official journal of the International Mammalian Genome Society, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed.
- Visualization and quantification of rDNA instabilities in mammalian cells and mouse models.Nucleic acids research · 2026Article
- Comparative analysis and classification of highly divergent mouse rDNA units based on their intergenic spacer (IGS) variability.NAR genomics and bioinformatics · 2024Article
- The chromatin landscape of the ribosomal RNA genes in mouse and human.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2019Review
- Robertsonian chromosomes and the nuclear architecture of mouse meiotic prophase spermatocytes.Biological research · 2014Article
- Chromosomal dynamics of nucleolar organizer regions (NORs) in the house mouse: micro-evolutionary insights.Heredity · 2012Article
- DNA methyltransferase inhibition may limit cancer cell growth by disrupting ribosome biogenesis.Epigenetics · 2011Article
- Chromatin association and regulation of rDNA transcription by the Ras-family protein RasL11a.The EMBO journal · 2010Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
The organization of ribosomal RNA genes (rDNA) in the genome of the mouse varies significantly from one strain to another, but has been shown to follow the pattern of clusters of tandem repeats located at chromosome ends, often associated with cytological nucleolus organizer regions. The number of copies of the repeat unit at each locus also varies. A probe for the 18S ribosomal RNA sequence on Southern blots reveals both high copy number bands and fainter bands indicative of low repeat number. We have mapped a number of newly identified low-copy-number rDNA loci in C57BL/6J, in addition to placing some of the NOR-associated rDNA repeats on the Jackson interspecific backcross (BSS) map. We suggest that additional low-copy-number loci may remain to be mapped, and that the evolution of rDNA loci in the genome may include the proliferation of single copies by retroinsertion or other mechanisms.
Indexed as
Identifiers
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Registered trials
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