Evidence map›Paper›PMID 8993858›Full record

ReviewClinical microbiology reviews1997

Yersinia pestis--etiologic agent of plague.

R D Perry, J D Fetherston

Open access · greenAbstract readHistorical ArticleReview
In one paragraph

Review in Clinical microbiology reviews, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 807 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
807citing papers in PubMed, 1 pooled it
18.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

807 citing papers in PubMed, 1 synthesis or guideline pooled it, 1,843 citations in OpenAlex.

  1. Pooled it
  2. Article
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  7. Article
  8. In Vitro Selection of Antibodies TargetingPathogens (Basel, Switzerland) · 2026
    Article
  9. Article
  10. Review
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  13. Emergence, global dispersal, and local adaptations ofApplied and environmental microbiology · 2026
    Review
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  16. Journal of bacteriology · 2026
    Article
  17. Article
  18. Article
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  20. Review

747 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

R D PerryDepartment of Microbiology and Immunology, University of Kentucky, Lexington 40536, USA. rperry@pop.uky.edu
J D Fetherston
University of Kentucky · US

Funding

Yersiniabactin and plague pathogenesisR01AI033481 · NIAID · UNIVERSITY OF KENTUCKY · PI PERRY, ROBERT DONALD · 1993 to 2013
$3.6M
Plague biofilm formation--regulation and functionR01AI025098 · NIAID · UNIVERSITY OF KENTUCKY · PI PERRY, ROBERT DONALD · 1993 to 2013
$2.9M
Yersiniabactin and plague pathogenesisR56AI033481 · NIAID · UNIVERSITY OF KENTUCKY · PI PERRY, ROBERT DONALD · 2008 to 2008
$366k
IRON STORAGE AND UPTAKE IN YERSINIA PESTISR29AI025098 · NIAID · UNIVERSITY OF KENTUCKY · PI PERRY, ROBERT DONALD · 1988 to 1992
–
NIAID NIH HHS AI25098NIAID NIH HHS AI33481
6 · The paper itself

Abstract

Plague is a widespread zoonotic disease that is caused by Yersinia pestis and has had devastating effects on the human population throughout history. Disappearance of the disease is unlikely due to the wide range of mammalian hosts and their attendant fleas. The flea/rodent life cycle of Y. pestis, a gram-negative obligate pathogen, exposes it to very different environmental conditions and has resulted in some novel traits facilitating transmission and infection. Studies characterizing virulence determinants of Y. pestis have identified novel mechanisms for overcoming host defenses. Regulatory systems controlling the expression of some of these virulence factors have proven quite complex. These areas of research have provide new insights into the host-parasite relationship. This review will update our present understanding of the history, etiology, epidemiology, clinical aspects, and public health issues of plague.

Indexed as

Amino Acid SequenceAnimalsAnimals, DomesticAnimals, WildAnti-Bacterial AgentsAntigens, BacterialBacterial ToxinsDisease ReservoirsGene Expression Regulation, BacterialGenes, BacterialGlobal HealthHistory, 19th CenturyHistory, AncientHistory, MedievalHumansIncidenceAnti-Bacterial AgentsAntigens, BacterialBacterial Toxins

Identifiers

PMID8993858
PMCPMC172914
OpenAlexW2145912774

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.