ArticleProceedings of the National Academy of Sciences of the United States of America1997
An Arabidopsis photolyase mutant is hypersensitive to ultraviolet-B radiation.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
58 citing papers in PubMed, 181 citations in OpenAlex.
- Plant tolerance mechanisms to DNA-damaging UV stress.Journal of experimental botany · 2025Review
- UV-B Irradiation Does Not Promote Flowering inPlant direct · 2025Article
- How Histone Acetyltransferases Shape Plant Photomorphogenesis and UV Response.International journal of molecular sciences · 2024Review
- Poaceae plants transfer cyclobutane pyrimidine dimer photolyase to chloroplasts for ultraviolet-B resistance.Plant physiology · 2024Article
- Plant responses to UV-B radiation: signaling, acclimation and stress tolerance.Stress biology · 2022Review
- Positive selection and heat-response transcriptomes reveal adaptive features of the Brassicaceae desert model, Anastatica hierochuntica.The New phytologist · 2022Article
- Growth and Biosynthesis of Phenolic Compounds of Canola (Plants (Basel, Switzerland) · 2022Article
- UV Protection in the Cornea: Failure and Rescue.Biology · 2022Review
- A putative bifunctional CPD/ (6-4) photolyase from the cyanobacteriaFrontiers in microbiology · 2022Article
- Natural Variation among Arabidopsis Accessions in the Regulation of Flavonoid Metabolism and Stress Gene Expression by Combined UV Radiation and Cold.Plant & cell physiology · 2021Article
- Autophagy Contributes to the Quality Control of Leaf Mitochondria.Plant & cell physiology · 2021Article
- DNA photolyase from Antarctic marine bacterium3 Biotech · 2021Article
- Structural Aspects of DNA Repair and Recombination in Crop Improvement.Frontiers in genetics · 2020Review
- Entire Photodamaged Chloroplasts Are Transported to the Central Vacuole by Autophagy.The Plant cell · 2017Article
- Methyl-CpG binding domain protein acts to regulate the repair of cyclobutane pyrimidine dimers on rice DNA.Scientific reports · 2016Article
- DNA damage and repair in plants - from models to crops.Frontiers in plant science · 2015Review
- The regulation of UV-B responses by the circadian clock.Plant signaling & behavior · 2015Article
- UV-B inhibition of hypocotyl growth in etiolated Arabidopsis thaliana seedlings is a consequence of cell cycle arrest initiated by photodimer accumulation.Journal of experimental botany · 2014Article
- Article
- The UV-B photoreceptor UVR8: from structure to physiology.The Plant cell · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Photolyases are DNA repair enzymes that use energy from blue light to repair pyrimidine dimers. We report the isolation of an Arabidopsis thaliana mutant (uvr2-1) that is defective in photorepair of cyclobutylpyrimidine dimers (CPDs). Whereas uvr2-1 is indistinguishable from wild type in the absence of UV light, low UV-B levels inhibit growth and cause leaf necrosis. uvr2-1 is more sensitive to UV-B than wild type when placed under white light after UV-B treatment. In contrast, recovery in darkness or in light lacking photoreactivating blue light results in equal injury in uvr2-1 and wild type. The uvr2-1 mutant is unable to remove CPDs in vivo, and plant extracts lack detectable photolyase activity. This recessive mutation segregates as a single gene located near the top of chromosome 1, and is a structural gene mutation in the type II CPD photolyase PHR1. This mutant provides evidence that CPD photolyase is required for plant survival in the presence of UV-B light.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.