ReviewProceedings of the National Academy of Sciences of the United States of America1996
On the molecular basis and regulation of cellular capacitative calcium entry: roles for Trp proteins.
Review in Proceedings of the National Academy of Sciences of the United States of America, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 93 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
93 citing papers in PubMed, 376 citations in OpenAlex.
- Xerostomia and Its Cellular Targets.International journal of molecular sciences · 2023Review
- Piezo1, a novel therapeutic target to treat pulmonary arterial hypertension.Frontiers in physiology · 2023Article
- Assessing the Potency of the Novel Tocolytics 2-APB, Glycyl-H-1152, and HC-067047 in Pregnant Human Myometrium.Reproductive sciences (Thousand Oaks, Calif.) · 2023Article
- Termination of CaCell calcium · 2021Article
- Global transcriptome profile of the developmental principles of in vitro iPSC-to-motor neuron differentiation.BMC molecular and cell biology · 2021Article
- Involvement of TRPC1 and Cyclin D1 in Human Pulmonary Artery Smooth Muscle Cells Proliferation Induced by Cigarette Smoke Extract.Current medical science · 2020Article
- CaJournal of cell science · 2019Article
- TRPC3/6/7 Knockdown Protects the Brain from Cerebral Ischemia Injury via Astrocyte Apoptosis Inhibition and Effects on NF-кB Translocation.Molecular neurobiology · 2017Article
- Canonical Transient Receptor Potential Channels and Their Link with Cardio/Cerebro-Vascular Diseases.Biomolecules & therapeutics · 2017Review
- The functions of store-operated calcium channels.Biochimica et biophysica acta. Molecular cell research · 2017Review
- Deletion of TRPC6 Attenuates NMDA Receptor-Mediated CaFrontiers in neuroscience · 2017Article
- Review
- Calcium signaling in lacrimal glands.Cell calcium · 2014Review
- Agomelatine and duloxetine synergistically modulates apoptotic pathway by inhibiting oxidative stress triggered intracellular calcium entry in neuronal PC12 cells: role of TRPM2 and voltage-gated calcium channels.The Journal of membrane biology · 2014Article
- STIM and Orai isoform expression in pregnant human myometrium: a potential role in calcium signaling during pregnancy.Frontiers in physiology · 2014Article
- Molecular mechanism of TRP channels.Comprehensive Physiology · 2013Review
- On the role of endothelial TRPC3 channels in endothelial dysfunction and cardiovascular disease.Cardiovascular & hematological agents in medicinal chemistry · 2012Review
- Optical recording reveals novel properties of GSK1016790A-induced vanilloid transient receptor potential channel TRPV4 activity in primary human endothelial cells.Molecular pharmacology · 2012Article
- The Ca(2+) sensor stromal interaction molecule 1 (STIM1) is necessary and sufficient for the store-operated Ca(2+) entry function of transient receptor potential canonical (TRPC) 1 and 4 channels in endothelial cells.Molecular pharmacology · 2012Article
- Hypoxic pulmonary vasoconstriction.Physiological reviews · 2012Review
33 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 1 institution in 1 country.
Funding
Abstract
During the last 2 years, our laboratory has worked on the elucidation of the molecular basis of capacitative calcium entry (CCE) into cells. Specifically, we tested the hypothesis that CCE channels are formed of subunits encoded in genes related to the Drosophila trp gene. The first step in this pursuit was to search for mammalian trp genes. We found not one but six mammalian genes and cloned several of their cDNAs, some in their full length. As assayed in mammalian cells, overexpression of some mammalian Trps increases CCE, while expression of partial trp cDNAs in antisense orientation can interfere with endogenous CCE. These findings provided a firm connection between CCE and mammalian Trps. This article reviews the known forms of CCE and highlights unanswered questions in our understanding of intracellular Ca2+ homeostasis and the physiological roles of CCE.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.