ArticleJournal of virology1997
A sorting motif localizes the foamy virus glycoprotein to the endoplasmic reticulum.
Article in Journal of virology, 1997. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
42 citing papers in PubMed, 66 citations in OpenAlex.
- An interaction between β'-COP and the ArfGAP, Glo3, maintains post-Golgi cargo recycling.The Journal of cell biology · 2023Article
- Strength in Diversity: Nuclear Export of Viral RNAs.Viruses · 2020Review
- Isolation of an Equine Foamy Virus and Sero-Epidemiology of the Viral Infection in Horses in Japan.Viruses · 2019Article
- Cocirculation of Two env Molecular Variants, of Possible Recombinant Origin, in Gorilla and Chimpanzee Simian Foamy Virus Strains from Central Africa.Journal of virology · 2015Article
- Non-simian foamy viruses: molecular virology, tropism and prevalence and zoonotic/interspecies transmission.Viruses · 2013Review
- Molecular basis for recognition of dilysine trafficking motifs by COPI.Developmental cell · 2012Article
- Review
- Subviral particle release determinants of prototype foamy virus.Journal of virology · 2008Article
- Foamy virus capsid assembly occurs at a pericentriolar region through a cytoplasmic targeting/retention signal in Gag.Traffic (Copenhagen, Denmark) · 2006Article
- Interactions between virus proteins and host cell membranes during the viral life cycle.International review of cytology · 2005Review
- Intracellular targeting signals contribute to localization of coronavirus spike proteins near the virus assembly site.Journal of virology · 2004Article
- Structural and evolutionary analysis of an orangutan foamy virus.Journal of virology · 2003Article
- Replication-competent hybrids between murine leukemia virus and foamy virus.Journal of virology · 2003Article
- Foamy virus envelope glycoprotein-mediated entry involves a pH-dependent fusion process.Journal of virology · 2003Article
- Foamy virus envelope glycoprotein is sufficient for particle budding and release.Journal of virology · 2003Article
- Further characterization of equine foamy virus reveals unusual features among the foamy viruses.Journal of virology · 2002Article
- Identification of a conserved residue of foamy virus Gag required for intracellular capsid assembly.Journal of virology · 2001Article
- A particle-associated glycoprotein signal peptide essential for virus maturation and infectivity.Journal of virology · 2001Article
- Historical perspective of foamy virus epidemiology and infection.Clinical microbiology reviews · 2001Review
- Immobilization of the early secretory pathway by a virus glycoprotein that binds to microtubules.The EMBO journal · 2000Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
We recently identified an endoplasmic reticulum (ER) retrieval signal-the dilysine motif-in the glycoproteins of all five foamy viruses (FVs) for which sequences were available (P. A. Goepfert, G. Wang, and M. J. Mulligan, Cell 82:543-544, 1995). In the present study, expression of recombinant human FV (HFV) glycoprotein and analyses of oligosaccharide modifications and precursor cleavage indicated that the protein was localized to the ER. HFV glycoproteins encoding seven different dilysine motif mutations were then expressed. The results indicated that disruptions of the dilysine motif resulted in higher levels of forward transport of the HFV glycoprotein from the ER through the Golgi apparatus to the plasma membrane. We conclude that the dilysine motif is responsible for ER sorting of the FV glycoprotein. Signal-mediated ER localization has not previously been described for a retroviral glycoprotein.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.