Evidence map›Paper›PMID 8983604›Full record

ReviewThe British journal of surgery1996

Sepsis and fat metabolism.

J S Samra, L K Summers, K N Frayn

Open access · greenAbstract readReview
In one paragraph

Review in The British journal of surgery, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 72 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Pseudomonas aeruginosa-derived pyocyanin reduces adipocyte differentiation, body weight, and fat mass as mechanisms contributing to septic cachexia.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2019
    Article
  6. Article
  7. Monitoring CO2 in shock states.Journal of clinical monitoring and computing · 2015
    Review
  8. Sepsis of unknown origin with multiorgan failure syndrome: Think of hemophagocytic lymphohistiocytosis.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2015
    Article
  9. Article
  10. Article
  11. Article
  12. NKT cells in sepsis.Clinical & developmental immunology · 2010
    Review
  13. Article
  14. Article
  15. Critical Appraisal of Bidirectional Relationship between Periodontitis and Hyperlipidemia.Journal of International Society of Preventive & Community Dentistry
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

J S SamraNuffield Department of Clinical Medicine, Radcliffe Infirmary, Oxford, UK.
L K Summers
K N Frayn
University of Oxford · GB

Funding

Wellcome Trust
6 · The paper itself

Abstract

Sepsis is a common surgical problem which can induce profound changes in the plasma concentrations of cytokines and hormones, leading to a catabolic state. Hypertriglyceridaemia and increased fat oxidation are the main features of altered fat metabolism encountered in this state. The endogenous catabolism of sepsis can be reduced by administering exogenous lipid emulsions as a source of metabolic fuel, although the changes in lipid metabolism associated with sepsis may affect the handling of these exogenous lipids. An exciting area for future research is an examination of the ability of lipid emulsions to reduce the morbidity and mortality associated with sepsis by altering immune responses, in addition to limiting catabolism.

Indexed as

Lipid MetabolismAdipose TissueCytokinesEndotoxinsHumansHypertriglyceridemiaSepsisCytokinesEndotoxins

Identifiers

PMID8983604
PMCPMC11440814
OpenAlexW2168749474

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.