Evidence map›Paper›PMID 8980489›Full record

ReviewPlant molecular biology1996

Optimizing expression of transgenes with an emphasis on post-transcriptional events.

M G Koziel, N B Carozzi, N Desai

Abstract readReview
PubMed Publisher
In one paragraph

Review in Plant molecular biology, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. From Structure to Function of Promoters and 5'UTRs in Maize.International journal of molecular sciences · 2026
    Review
  2. Scaled codon usage similarity index: A comprehensive resource for crop plants.Journal, genetic engineering & biotechnology · 2024
    Article
  3. Article
  4. Article
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  6. Site-targeted mutagenesis for stabilization of recombinant monoclonal antibody expressed in tobacco (Nicotiana tabacum) plants.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2016
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Folate biofortification of tomato fruit.Proceedings of the National Academy of Sciences of the United States of America · 2007
    Article
  15. Article
  16. Article
  17. Nucleotide polymorphism in the Adh2 region of the wild rice Oryza rufipogon.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2005
    Article
  18. Article
  19. Folate biofortification in tomatoes by engineering the pteridine branch of folate synthesis.Proceedings of the National Academy of Sciences of the United States of America · 2004
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

M G KozielCiba Agricultural Biotechnology Unit, Research Triangle Park, NC 27709, USA.
N B Carozzi
N Desai

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introducing a foreign gene into a new plant host does not always result in a high level of expression of the incoming gene. Numerous promoters have been used to express foreign genes in different plant tissues, but there are sometime various features of the new gene which are deleterious to expression in the new host. There are a number of post-transcriptional steps in the expression of a gene and sometimes sequences present in a particular coding region can resemble the signals which initiate these processing steps. When aberrantly carried out, these steps diminish the level of expression. By removing such fortuitous signals, one can dramatically increase expression of a transgene in plants. Ensuring proper protein folding and/or targeting the protein product to a particular cellular compartment can also be used to increase the level of protein obtained. The various methods used to optimize expression of a foreign gene in plants by concentrating on post-transcriptional events are discussed.

Indexed as

Gene Expression Regulation, PlantRNA Processing, Post-TranscriptionalTransgenesChloroplastsGene Expression Regulation, BacterialGenes, BacterialGenes, SyntheticIntronsProtein Folding

Identifiers

PMID8980489

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.