Evidence map›Paper›PMID 8978059›Full record

ArticleGenetics1996

Identification of selected gamma-ray induced deficiencies in zebrafish using multiplex polymerase chain reaction.

A Fritz, M Rozowski, C Walker, M Westerfield

Abstract read
In one paragraph

Article in Genetics, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Zebrafish as a model for kidney function and disease.Pediatric nephrology (Berlin, Germany) · 2019
    Review
  4. Article
  5. Article
  6. Close association of olfactory placode precursors and cranial neural crest cells does not predestine cell mixing.Developmental dynamics : an official publication of the American Association of Anatomists · 2012
    Article
  7. Article
  8. Reverse genetics in zebrafish by TILLING.Briefings in functional genomics & proteomics · 2008
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. The role of thyroid hormone in zebrafish and axolotl development.Proceedings of the National Academy of Sciences of the United States of America · 1997
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

A FritzInstitute of Neuroscience, University of Oregon, Eugene 97403, USA. fritz@uoneuro.uoregon.edu
M Rozowski
C Walker
M Westerfield

Funding

Zebrafish FacilityP01HD022486 · NICHD · UNIVERSITY OF OREGON · PI EISEN, JUDITH S · 1987 to 2017
$28.8M
NICHD NIH HHS HD-22486
6 · The paper itself

Abstract

The ease with which mutations can be generated in zebrafish makes this vertebrate an important resource for developmental genetics and genome studies. We have developed a PCR-based screening method that allows the efficient identification of gamma-ray induced deficiencies targeted to selected sequences. We describe three mutants characteristic of our findings and show that these mutations include deletions and translocations that can affect as much as 1% of the genome. These deficiencies provide a basis for analyzing the functions of cloned zebrafish genes using noncomplementation screens for point mutations induced by high-efficiency chemical mutagenesis.

Indexed as

AnimalsDNA PrimersGamma RaysMutationPolymerase Chain ReactionZebrafishDNA Primers

Identifiers

PMID8978059
PMCPMC1207723

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.